1zww

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1zww.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1zww.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1zww| PDB=1zww | SCENE= }}
{{STRUCTURE_1zww| PDB=1zww | SCENE= }}
-
'''Crystal structure of endophilin-A1 BAR domain'''
+
===Crystal structure of endophilin-A1 BAR domain===
-
==Overview==
+
<!--
-
Endophilin has been implicated in the retrieval of membrane via endocytosis of clathrin-coated vesicles, which is crucial for the maintenance of neurotransmitter exocytosis during stimulation; both exocytosis and endocytosis are regulated by intracellular calcium levels. Here, we present the 2.3 A crystal structure of the endophilin-A1 BAR domain, which has been suggested to function in inducing and sensing membrane curvature at the site of endocytosis. Endo-BAR folds into a crescent-shaped dimer composed of two elongated, three-helix bundles. Two additional domains of 30 residues each, inserted into helix 1 at the center of the concave side of the dimer, may interfere with the proposed mode of BAR domain membrane interaction. In addition, the dimer binds 11 divalent cadmium ions in the crystal mostly with typical Ca2+ co-ordination spheres. The endophilin-1A BAR domain thus constitutes a new variant of a BAR domain, and it may link endophilin-1A BAR function to calcium regulation of endocytosis.
+
The line below this paragraph, {{ABSTRACT_PUBMED_16023669}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 16023669 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_16023669}}
==About this Structure==
==About this Structure==
Line 24: Line 28:
[[Category: Weissenhorn, W.]]
[[Category: Weissenhorn, W.]]
[[Category: Coiled coil]]
[[Category: Coiled coil]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:10:40 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 01:12:42 2008''

Revision as of 22:12, 28 July 2008

Image:1zww.png

Template:STRUCTURE 1zww

Crystal structure of endophilin-A1 BAR domain

Template:ABSTRACT PUBMED 16023669

About this Structure

1ZWW is a Single protein structure of sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

Crystal structure of the endophilin-A1 BAR domain., Weissenhorn W, J Mol Biol. 2005 Aug 19;351(3):653-61. PMID:16023669

Page seeded by OCA on Tue Jul 29 01:12:42 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1zww"
Personal tools