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211d

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{{STRUCTURE_211d| PDB=211d | SCENE= }}
{{STRUCTURE_211d| PDB=211d | SCENE= }}
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'''THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE'''
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===THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE===
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==Overview==
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The three-dimensional structure of d[CGTA'CG], where A' = [2-NH2-A], was determined to atomic (1.35 A) resolution by single isomorphous replacement. The d[CGTA'CG] hexamer crystallizes in space group P3221, and is not isomorphous with other DNA hexanucleotides. Despite completely different crystal packing, the essential characteristics of the Z-DNA conformation are maintained. The structure was determined by single isomorphous replacement using a triammine platinum fragment. Thus, this study also demonstrates, for the first time, the feasibility of the use of this reagent for the direct phasing of DNA crystal structures.
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(as it appears on PubMed at http://www.pubmed.gov), where 7492550 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7492550}}
==About this Structure==
==About this Structure==
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[[Category: Modified]]
[[Category: Modified]]
[[Category: Z-dna]]
[[Category: Z-dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:18:35 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 14:35:58 2008''

Revision as of 11:36, 27 July 2008

Template:STRUCTURE 211d

THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE

Template:ABSTRACT PUBMED 7492550

About this Structure

Full crystallographic information is available from OCA.

Reference

Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative., Parkinson GN, Arvanitis GM, Lessinger L, Ginell SL, Jones R, Gaffney B, Berman HM, Biochemistry. 1995 Nov 28;34(47):15487-95. PMID:7492550

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