This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2ac1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2ac1.gif|left|200px]]
+
{{Seed}}
 +
[[Image:2ac1.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2ac1| PDB=2ac1 | SCENE= }}
{{STRUCTURE_2ac1| PDB=2ac1 | SCENE= }}
-
'''Crystal structure of a cell-wall invertase from Arabidopsis thaliana'''
+
===Crystal structure of a cell-wall invertase from Arabidopsis thaliana===
-
==Overview==
+
<!--
-
Cell-wall invertases play crucial roles during plant development. They hydrolyse sucrose into its fructose and glucose subunits by cleavage of the alpha1-beta2 glycosidic bond. Here, the structure of the Arabidopsis thaliana cell-wall invertase 1 (AtcwINV1; gene accession code At3g13790) is described at a resolution of 2.15 A. The structure comprises an N-terminal fivefold beta-propeller domain followed by a C-terminal domain formed by two beta-sheets. The active site is positioned in the fivefold beta-propeller domain, containing the nucleophile Asp23 and the acid/base catalyst Glu203 of the double-displacement enzymatic reaction. The function of the C-terminal domain remains unknown. Unlike in other GH 32 family enzyme structures known to date, in AtcwINV1 the cleft formed between both domains is blocked by Asn299-linked carbohydrates. A preliminary site-directed mutagenesis experiment (Asn299Asp) removed the glycosyl chain but did not alter the activity profile of the enzyme.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17139091}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17139091 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17139091}}
==About this Structure==
==About this Structure==
Line 30: Line 34:
[[Category: Verhaest, M.]]
[[Category: Verhaest, M.]]
[[Category: Five fold beta propeller]]
[[Category: Five fold beta propeller]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:51:55 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 10:06:20 2008''

Revision as of 07:06, 29 July 2008

Image:2ac1.png

Template:STRUCTURE 2ac1

Crystal structure of a cell-wall invertase from Arabidopsis thaliana

Template:ABSTRACT PUBMED 17139091

About this Structure

2AC1 is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

X-ray diffraction structure of a cell-wall invertase from Arabidopsis thaliana., Verhaest M, Lammens W, Le Roy K, De Coninck B, De Ranter CJ, Van Laere A, Van den Ende W, Rabijns A, Acta Crystallogr D Biol Crystallogr. 2006 Dec;62(Pt 12):1555-63. Epub 2006, Nov 23. PMID:17139091

Page seeded by OCA on Tue Jul 29 10:06:20 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ac1"
Personal tools