2agg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2agg.gif|left|200px]]
+
{{Seed}}
 +
[[Image:2agg.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2agg| PDB=2agg | SCENE= }}
{{STRUCTURE_2agg| PDB=2agg | SCENE= }}
-
'''succinyl-AAPK-trypsin acyl-enzyme at 1.28 A resolution'''
+
===succinyl-AAPK-trypsin acyl-enzyme at 1.28 A resolution===
-
==Overview==
+
<!--
-
Atomic resolution structures of trypsin acyl-enzymes and a tetrahedral intermediate analog, along with previously solved structures representing the Michaelis complex, are used to reconstruct events in the catalytic cycle of this classic serine protease. Structural comparisons provide insight into active site adjustments involved in catalysis. Subtle motions of the catalytic serine and histidine residues coordinated with translation of the substrate reaction center are seen to favor the forward progress of the acylation reaction. The structures also clarify the attack trajectory of the hydrolytic water in the deacylation reaction.
+
The line below this paragraph, {{ABSTRACT_PUBMED_16636277}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 16636277 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_16636277}}
==About this Structure==
==About this Structure==
Line 32: Line 36:
[[Category: Proteinase]]
[[Category: Proteinase]]
[[Category: Serine protease]]
[[Category: Serine protease]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 19:01:10 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 07:05:01 2008''

Revision as of 04:05, 28 July 2008

Image:2agg.png


PDB ID 2agg

Drag the structure with the mouse to rotate
2agg, resolution 1.28Å ()
Ligands: ,
Non-Standard Residues:
Activity: Trypsin, with EC number 3.4.21.4
Related: 2age, 2agi, 2ah4
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



succinyl-AAPK-trypsin acyl-enzyme at 1.28 A resolution

Template:ABSTRACT PUBMED 16636277

About this Structure

2AGG is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates., Radisky ES, Lee JM, Lu CJ, Koshland DE Jr, Proc Natl Acad Sci U S A. 2006 May 2;103(18):6835-40. Epub 2006 Apr 24. PMID:16636277

Page seeded by OCA on Mon Jul 28 07:05:01 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2agg"
Personal tools