This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2ak2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2ak2.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:2ak2.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2ak2| PDB=2ak2 | SCENE= }}
{{STRUCTURE_2ak2| PDB=2ak2 | SCENE= }}
-
'''ADENYLATE KINASE ISOENZYME-2'''
+
===ADENYLATE KINASE ISOENZYME-2===
-
==Overview==
+
<!--
-
In vertebrates, there are different adenylate kinases in the compartments cytosol, mitochondrial intermembrane space, and mitochondrial matrix. Here, we report the spatial structure of the intermembrane species established in two crystal forms by X-ray diffraction analyses at 1.92 and 2.1 A resolution. In both structures, the enzyme is unligated, and thus in an "open" conformation. The enzyme was prepared from bovine liver, containing at least five variants arisen from posttranscriptional and posttranslational modifications. It could only be crystallized after removing some of these variants. A comparison with the known structures of the adenylate kinases from cytosol and mitochondrial matrix reveals structural differences that should play a role in protein targeting because none of these enzymes contains a cleavable signal peptide. A further comparison with adenylate kinases from Gram-positive bacteria showed that the structural Zn2+ ion of these species is replaced by a strictly conserved assembly of hydrogen bonded residues.
+
The line below this paragraph, {{ABSTRACT_PUBMED_8868479}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 8868479 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_8868479}}
==About this Structure==
==About this Structure==
Line 27: Line 31:
[[Category: Nucleoside monophosphate kinase]]
[[Category: Nucleoside monophosphate kinase]]
[[Category: Phosphotransferase]]
[[Category: Phosphotransferase]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 19:08:54 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 17:50:27 2008''

Revision as of 14:50, 27 July 2008

Image:2ak2.png

Template:STRUCTURE 2ak2

ADENYLATE KINASE ISOENZYME-2

Template:ABSTRACT PUBMED 8868479

About this Structure

2AK2 is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

The structure of bovine mitochondrial adenylate kinase: comparison with isoenzymes in other compartments., Schlauderer GJ, Schulz GE, Protein Sci. 1996 Mar;5(3):434-41. PMID:8868479

Page seeded by OCA on Sun Jul 27 17:50:27 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ak2"
Personal tools