2ar6

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{{STRUCTURE_2ar6| PDB=2ar6 | SCENE= }}
{{STRUCTURE_2ar6| PDB=2ar6 | SCENE= }}
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'''Pterocarpus angolensis Lectin (PAL) In Complex With The Pentasaccharide M592'''
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===Pterocarpus angolensis Lectin (PAL) In Complex With The Pentasaccharide M592===
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==Overview==
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The crystal structure of Pterocarpus angolensis lectin is determined in its ligand-free state, in complex with the fucosylated biantennary complex type decasaccharide NA2F, and in complex with a series of smaller oligosaccharide constituents of NA2F. These results together with thermodynamic binding data indicate that the complete oligosaccharide binding site of the lectin consists of five subsites allowing the specific recognition of the pentasaccharide GlcNAc beta(1-2)Man alpha(1-3)[GlcNAc beta(1-2)Man alpha(1-6)]Man. The mannose on the 1-6 arm occupies the monosaccharide binding site while the GlcNAc residue on this arm occupies a subsite that is almost identical to that of concanavalin A (con A). The core mannose and the GlcNAc beta(1-2)Man moiety on the 1-3 arm on the other hand occupy a series of subsites distinct from those of con A.
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(as it appears on PubMed at http://www.pubmed.gov), where 16704415 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16704415}}
==About this Structure==
==About this Structure==
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[[Category: Carbohydrate recognition]]
[[Category: Carbohydrate recognition]]
[[Category: Lectin]]
[[Category: Lectin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 23:55:02 2008''

Revision as of 20:55, 28 July 2008

Image:2ar6.png

Template:STRUCTURE 2ar6

Pterocarpus angolensis Lectin (PAL) In Complex With The Pentasaccharide M592

Template:ABSTRACT PUBMED 16704415

About this Structure

2AR6 is a Single protein structure of sequence from Pterocarpus angolensis. Full crystallographic information is available from OCA.

Reference

Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin., Buts L, Garcia-Pino A, Imberty A, Amiot N, Boons GJ, Beeckmans S, Versees W, Wyns L, Loris R, FEBS J. 2006 Jun;273(11):2407-20. PMID:16704415

Page seeded by OCA on Mon Jul 28 23:55:02 2008

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