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2ivf
From Proteopedia
(New page: 200px<br /> <applet load="2ivf" size="450" color="white" frame="true" align="right" spinBox="true" caption="2ivf, resolution 1.88Å" /> '''ETHYLBENZENE DEHYDR...) |
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==About this Structure== | ==About this Structure== | ||
| - | 2IVF is a [[http://en.wikipedia.org/wiki/Protein_complex Protein complex]] structure of sequences from [[http://en.wikipedia.org/wiki/Azoarcus_sp._eb1 Azoarcus sp. eb1]] with ACT, PO4, MES, SF4, MO, MGD, MD1, F3S, HEM and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.99.2 1.17.99.2]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2IVF OCA]]. | + | 2IVF is a [[http://en.wikipedia.org/wiki/Protein_complex Protein complex]] structure of sequences from [[http://en.wikipedia.org/wiki/Azoarcus_sp._eb1 Azoarcus sp. eb1]] with ACT, PO4, MES, SF4, MO, MGD, MD1, F3S, HEM and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Ethylbenzene_hydroxylase Ethylbenzene hydroxylase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.99.2 1.17.99.2]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2IVF OCA]]. |
==Reference== | ==Reference== | ||
Crystal structure of ethylbenzene dehydrogenase from Aromatoleum aromaticum., Kloer DP, Hagel C, Heider J, Schulz GE, Structure. 2006 Sep;14(9):1377-88. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16962969 16962969] | Crystal structure of ethylbenzene dehydrogenase from Aromatoleum aromaticum., Kloer DP, Hagel C, Heider J, Schulz GE, Structure. 2006 Sep;14(9):1377-88. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16962969 16962969] | ||
[[Category: Azoarcus sp. eb1]] | [[Category: Azoarcus sp. eb1]] | ||
| + | [[Category: Ethylbenzene hydroxylase]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Hagel, C.]] | [[Category: Hagel, C.]] | ||
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[[Category: oxidoreductase]] | [[Category: oxidoreductase]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:09:27 2007'' |
Revision as of 10:04, 30 October 2007
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ETHYLBENZENE DEHYDROGENASE FROM AROMATOLEUM AROMATICUM
Overview
Anaerobic degradation of hydrocarbons was discovered a decade ago, and, ethylbenzene dehydrogenase was one of the first characterized enzymes, involved. The structure of the soluble periplasmic 165 kDa enzyme was, established at 1.88 A resolution. It is a heterotrimer. The alpha subunit, contains the catalytic center with a molybdenum held by two, molybdopterin-guanine dinucleotides, one with an open pyran ring, and an, iron-sulfur cluster with a histidine ligand. During catalysis, electrons, produced by substrate oxidation are transferred to a heme in the gamma, subunit and then presumably to a separate cytochrome involved in nitrate, respiration. The beta subunit contains four iron-sulfur clusters and is, structurally related to ferredoxins. The gamma subunit is the first known, protein ... [(full description)]
About this Structure
2IVF is a [Protein complex] structure of sequences from [Azoarcus sp. eb1] with ACT, PO4, MES, SF4, MO, MGD, MD1, F3S, HEM and GOL as [ligands]. Active as [Ethylbenzene hydroxylase], with EC number [1.17.99.2]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Crystal structure of ethylbenzene dehydrogenase from Aromatoleum aromaticum., Kloer DP, Hagel C, Heider J, Schulz GE, Structure. 2006 Sep;14(9):1377-88. PMID:16962969
Page seeded by OCA on Tue Oct 30 12:09:27 2007
Categories: Azoarcus sp. eb1 | Ethylbenzene hydroxylase | Protein complex | Hagel, C. | Heider, J. | Kloer, D.P. | Schulz, G.E. | ACT | F3S | GOL | HEM | MD1 | MES | MGD | MO | PO4 | SF4 | Anaerobic hydrocarbon degradation | Dmso reductase family | Fe/s cluster | Mo-bismgd enzyme | Moco | Oxidoreductase
