This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2bmz

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2bmz.gif|left|200px]]
+
{{Seed}}
 +
[[Image:2bmz.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2bmz| PDB=2bmz | SCENE= }}
{{STRUCTURE_2bmz| PDB=2bmz | SCENE= }}
-
'''BANANA LECTIN BOUND TO XYL-B1,3 MAN-A-O-METHYL (XM)'''
+
===BANANA LECTIN BOUND TO XYL-B1,3 MAN-A-O-METHYL (XM)===
-
==Overview==
+
<!--
-
Banana lectin (Banlec) is a dimeric plant lectin from the jacalin-related lectin family. Banlec belongs to a subgroup of this family that binds to glucose/mannose, but is unique in recognizing internal alpha1,3 linkages as well as beta1,3 linkages at the reducing termini. Here we present the crystal structures of Banlec alone and with laminaribiose (LAM) (Glcbeta1, 3Glc) and Xyl-beta1,3-Man-alpha-O-Methyl. The structure of Banlec has a beta-prism-I fold, similar to other family members, but differs from them in its mode of sugar binding. The reducing unit of the sugar is inserted into the binding site causing the second saccharide unit to be placed in the opposite orientation compared with the other ligand-bound structures of family members. More importantly, our structures reveal the presence of a second sugar binding site that has not been previously reported in the literature. The residues involved in the second site are common to other lectins in this family, potentially signaling a new group of mannose-specific jacalin-related lectins (mJRL) with two sugar binding sites.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15944373}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15944373 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15944373}}
==About this Structure==
==About this Structure==
Line 30: Line 34:
[[Category: Lectin]]
[[Category: Lectin]]
[[Category: Mannose-specific jacalin-related lectin]]
[[Category: Mannose-specific jacalin-related lectin]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 20:30:55 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 13:20:26 2008''

Revision as of 10:20, 27 July 2008

Image:2bmz.png

Template:STRUCTURE 2bmz

BANANA LECTIN BOUND TO XYL-B1,3 MAN-A-O-METHYL (XM)

Template:ABSTRACT PUBMED 15944373

About this Structure

2BMZ is a Single protein structure of sequence from Musa acuminata. Full crystallographic information is available from OCA.

Reference

Crystal structure of banana lectin reveals a novel second sugar binding site., Meagher JL, Winter HC, Ezell P, Goldstein IJ, Stuckey JA, Glycobiology. 2005 Oct;15(10):1033-42. Epub 2005 Jun 8. PMID:15944373

Page seeded by OCA on Sun Jul 27 13:20:26 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2bmz"
Personal tools