2bzu

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[[Image:2bzu.gif|left|200px]]
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{{STRUCTURE_2bzu| PDB=2bzu | SCENE= }}
{{STRUCTURE_2bzu| PDB=2bzu | SCENE= }}
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'''HUMAN ADENOVIRUS SEROTYPE 41 FIBER HEAD'''
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===HUMAN ADENOVIRUS SEROTYPE 41 FIBER HEAD===
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==Overview==
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Human enteric adenoviruses of species F contain two fibers in the same virion, a long fiber which binds to coxsackievirus and adenovirus receptor (CAR) and a short fiber of unknown function. We have determined the high-resolution crystal structure of the short fiber head of human adenovirus serotype 41 (Ad41). The short fiber head has the characteristic fold of other known fiber heads but has three unusual features. First, it has much shorter loops between the beta-strands. Second, one of the usually well-ordered beta-strands on the distal face of the fiber head is highly disordered and this same region is sensitive to digestion with pepsin, an enzyme occurring naturally in the intestinal tract, the physiological environment of Ad41. Third, the AB loop has a deletion giving it a distinct conformation incompatible with CAR binding.
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The line below this paragraph, {{ABSTRACT_PUBMED_16254343}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 16254343 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16254343}}
==About this Structure==
==About this Structure==
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[[Category: Receptor]]
[[Category: Receptor]]
[[Category: Viral protein]]
[[Category: Viral protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 21:01:42 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:49:55 2008''

Revision as of 17:50, 28 July 2008

Template:STRUCTURE 2bzu

HUMAN ADENOVIRUS SEROTYPE 41 FIBER HEAD

Template:ABSTRACT PUBMED 16254343

About this Structure

2BZU is a Single protein structure of sequence from Human adenovirus 41. Full crystallographic information is available from OCA.

Reference

Crystal structure of enteric adenovirus serotype 41 short fiber head., Seiradake E, Cusack S, J Virol. 2005 Nov;79(22):14088-94. PMID:16254343

Page seeded by OCA on Mon Jul 28 20:49:55 2008

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