2cag

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[[Image:2cag.gif|left|200px]]
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[[Image:2cag.png|left|200px]]
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==Overview==
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{{ABSTRACT_8901874}}
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Various enzymes use semi-stable ferryl intermediates and free radicals during their catalytic cycle, amongst them haem catalases. Structures for two transient intermediates (compounds I and II) of the NADPH-dependent catalase from Proteus mirabilis (PMC) have been determined by time-resolved X-ray crystallography and single crystal microspectrophotometry. The results show the formation and transformation of the ferryl group in the haem, and the unexpected binding of an anion during this reaction at a site distant from the haem.
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==About this Structure==
==About this Structure==
2CAG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Proteus_mirabilis Proteus mirabilis]. The following page contains interesting information on the relation of 2CAG with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb57_1.html Catalase]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CAG OCA].
2CAG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Proteus_mirabilis Proteus mirabilis]. The following page contains interesting information on the relation of 2CAG with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb57_1.html Catalase]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CAG OCA].
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==Reference==
 
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Ferryl intermediates of catalase captured by time-resolved Weissenberg crystallography and UV-VIS spectroscopy., Gouet P, Jouve HM, Williams PA, Andersson I, Andreoletti P, Nussaume L, Hajdu J, Nat Struct Biol. 1996 Nov;3(11):951-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8901874 8901874]
 
[[Category: Catalase]]
[[Category: Catalase]]
[[Category: Proteus mirabilis]]
[[Category: Proteus mirabilis]]
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[[Category: Nadp]]
[[Category: Nadp]]
[[Category: Peroxidase]]
[[Category: Peroxidase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 21:34:35 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 26 18:14:04 2008''

Revision as of 15:14, 26 June 2008

Image:2cag.png

Template:STRUCTURE 2cag

CATALASE COMPOUND II


Template:ABSTRACT 8901874

About this Structure

2CAG is a Single protein structure of sequence from Proteus mirabilis. The following page contains interesting information on the relation of 2CAG with [Catalase]. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Jun 26 18:14:04 2008

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