2d00

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[[Image:2d00.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_2d00| PDB=2d00 | SCENE= }}
{{STRUCTURE_2d00| PDB=2d00 | SCENE= }}
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'''Subunit F of V-type ATPase/synthase'''
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===Subunit F of V-type ATPase/synthase===
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==Overview==
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The crystal structure of subunit F of vacuole-type ATPase/synthase (prokaryotic V-ATPase) was determined to of 2.2 A resolution. The subunit reveals unexpected structural similarity to the response regulator proteins that include the Escherichia coli chemotaxis response regulator CheY. The structure was successfully placed into the low-resolution EM structure of the prokaryotic holo-V-ATPase at a location indicated by the results of crosslinking experiments. The crystal structure, together with the single-molecule analysis using fluorescence resonance energy transfer, showed that the subunit F exhibits two conformations, a 'retracted' form in the absence and an 'extended' form in the presence of ATP. Our results postulated that the subunit F is a regulatory subunit in the V-ATPase.
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The line below this paragraph, {{ABSTRACT_PUBMED_16281059}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 16281059 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16281059}}
==About this Structure==
==About this Structure==
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[[Category: Subunit f]]
[[Category: Subunit f]]
[[Category: V-atpase]]
[[Category: V-atpase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 23:26:38 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:55:31 2008''

Revision as of 21:55, 27 July 2008

Image:2d00.png

Template:STRUCTURE 2d00

Subunit F of V-type ATPase/synthase

Template:ABSTRACT PUBMED 16281059

About this Structure

2D00 is a Single protein structure of sequence from Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

Structure of a central stalk subunit F of prokaryotic V-type ATPase/synthase from Thermus thermophilus., Makyio H, Iino R, Ikeda C, Imamura H, Tamakoshi M, Iwata M, Stock D, Bernal RA, Carpenter EP, Yoshida M, Yokoyama K, Iwata S, EMBO J. 2005 Nov 16;24(22):3974-83. Epub 2005 Nov 10. PMID:16281059

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