2c3h
From Proteopedia
(New page: 200px<br /> <applet load="2c3h" size="450" color="white" frame="true" align="right" spinBox="true" caption="2c3h, resolution 2.24Å" /> '''STRUCTURE OF CBM26 ...) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2C3H is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bacillus_halodurans Bacillus halodurans]] with GLC and SO4 as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2C3H OCA]]. | + | 2C3H is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bacillus_halodurans Bacillus halodurans]] with GLC and SO4 as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2C3H OCA]]. |
==Reference== | ==Reference== | ||
| Line 30: | Line 30: | ||
[[Category: starch binding]] | [[Category: starch binding]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:12:31 2007'' |
Revision as of 10:07, 30 October 2007
|
STRUCTURE OF CBM26 FROM BACILLUS HALODURANS AMYLASE IN COMPLEX WITH MALTOSE
Overview
Starch-hydrolyzing enzymes lacking alpha-glucan-specific, carbohydrate-binding modules (CBMs) typically have lowered activity on, granular starch relative to their counterparts with CBMs. Thus, consideration of starch recognition by CBMs is a key factor in, understanding granular starch hydrolysis. To this end, we have dissected, the modular structure of the maltohexaose-forming amylase from Bacillus, halodurans (C-125). This five-module protein comprises an N-terminal, family 13 catalytic module followed in order by two modules of unknown, function, a family 26 CBM (BhCBM26), and a family 25 CBM (BhCBM25). Here, we present a comprehensive structure-function analysis of starch and, alpha-glucooligosaccharide recognition by BhCBM25 and BhCBM26 using UV, methods, isothermal titration ... [(full description)]
About this Structure
2C3H is a [Single protein] structure of sequence from [Bacillus halodurans] with GLC and SO4 as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
A structural and functional analysis of alpha-glucan recognition by family 25 and 26 carbohydrate-binding modules reveals a conserved mode of starch recognition., Boraston AB, Healey M, Klassen J, Ficko-Blean E, Lammerts van Bueren A, Law V, J Biol Chem. 2006 Jan 6;281(1):587-98. Epub 2005 Oct 17. PMID:16230347
Page seeded by OCA on Tue Oct 30 12:12:31 2007
