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2f87

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{{Seed}}
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{{STRUCTURE_2f87| PDB=2f87 | SCENE= }}
{{STRUCTURE_2f87| PDB=2f87 | SCENE= }}
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'''Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus'''
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===Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus===
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==Overview==
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The NMR structure of a 12-mer RNA derived from the helix 6 of SRP RNA from Pyrococcus furiosus, whose loop-closing base pair is U.G, was determined, and the structural and thermodynamic properties of the RNA were compared with those of a mutant RNA with the C:G closing base pair. Although the structures of the two RNAs are similar to each other and adopt the GNRR motif the conformational stabilities are significantly different to each other It was suggested that weaker stacking interaction of the GAAG loop with the U:G closing base pair in 12-mer RNA causes the lower conformational stability.
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The line below this paragraph, {{ABSTRACT_PUBMED_16838833}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 16838833 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16838833}}
==About this Structure==
==About this Structure==
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F87 OCA].
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Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F87 OCA].
==Reference==
==Reference==
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[[Category: Rna]]
[[Category: Rna]]
[[Category: Srp]]
[[Category: Srp]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 03:34:44 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:57:46 2008''

Revision as of 10:57, 29 July 2008

Image:2f87.png

Template:STRUCTURE 2f87

Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus

Template:ABSTRACT PUBMED 16838833

About this Structure

Full experimental information is available from OCA.

Reference

Solution structure of a GAAG tetraloop in helix 6 of SRP RNA from Pyrococcus furiosus., Okada K, Takahashi M, Sakamoto T, Kawai G, Nakamura K, Kanai A, Nucleosides Nucleotides Nucleic Acids. 2006;25(4-6):383-95. PMID:16838833

Page seeded by OCA on Tue Jul 29 13:57:46 2008

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