2fb4

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[[Image:2fb4.jpg|left|200px]]
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{{STRUCTURE_2fb4| PDB=2fb4 | SCENE= }}
{{STRUCTURE_2fb4| PDB=2fb4 | SCENE= }}
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'''DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L-KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN)'''
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===DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L-KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN)===
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==Overview==
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The immunoglobulin Kol was the first intact antibody molecule which was characterized by high-resolution X-ray crystallography. Furthermore the complete amino-acid sequence of the heavy (H)-chain is known. Here we report the complete amino-acid sequence of the light (L)-chain of the monoclonal immunoglobulin Kol (IgG1). The polypeptide has an Mr of 22,781, consists of 216 amino acids and due to its structure is of the lambda-type. With the characteristic amino acids threonine, asparagine, threonine, glycine and lysine in positions 101, 114, 116, 154, and 165, respectively the Kol L-chain is of the Mcg isotype. With the proteins Mcg, Mot, Bur, Loc and Mem six myeloma-derived amino-acid sequences of the same isotype are known. The amino-acid sequence of the N-terminal variable part is characteristic of subgroup 1. This contribution completes the primary structure of IgG1 Kol.
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(as it appears on PubMed at http://www.pubmed.gov), where 2713105 is the PubMed ID number.
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{{ABSTRACT_PUBMED_2713105}}
==About this Structure==
==About this Structure==
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[[Category: Marquart, M.]]
[[Category: Marquart, M.]]
[[Category: Immunoglobulin]]
[[Category: Immunoglobulin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 03:40:52 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 15:58:32 2008''

Revision as of 12:58, 28 July 2008

Image:2fb4.png

Template:STRUCTURE 2fb4

DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L-KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN)

Template:ABSTRACT PUBMED 2713105

About this Structure

2FB4 is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1fb4. Full crystallographic information is available from OCA.

Reference

[The primary structure of crystallizable monoclonal immunoglobulin IgG1 Kol. II. Amino acid sequence of the L-chain, gamma-type, subgroup I], Kratzin HD, Palm W, Stangel M, Schmidt WE, Friedrich J, Hilschmann N, Biol Chem Hoppe Seyler. 1989 Mar;370(3):263-72. PMID:2713105

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