2ffh

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{{STRUCTURE_2ffh| PDB=2ffh | SCENE= }}
{{STRUCTURE_2ffh| PDB=2ffh | SCENE= }}
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'''THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS'''
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===THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS===
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==Overview==
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The crystal structure of the signal sequence binding subunit of the signal recognition particle (SRP) from Thermus aquaticus reveals a deep groove bounded by a flexible loop and lined with side chains of conserved hydrophobic residues. The groove defines a flexible, hydrophobic environment that is likely to contribute to the structural plasticity necessary for SRP to bind signal sequences of different lengths and amino acid sequence. The structure also reveals a helix-turn-helix motif containing an arginine-rich alpha helix that is required for binding to SRP RNA and is implicated in forming the core of an extended RNA binding surface.
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(as it appears on PubMed at http://www.pubmed.gov), where 9695947 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9695947}}
==About this Structure==
==About this Structure==
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[[Category: Signal sequence-binding]]
[[Category: Signal sequence-binding]]
[[Category: Srp54]]
[[Category: Srp54]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 03:49:56 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:29:03 2008''

Revision as of 04:29, 29 July 2008

Image:2ffh.png

Template:STRUCTURE 2ffh

THE SIGNAL SEQUENCE BINDING PROTEIN FFH FROM THERMUS AQUATICUS

Template:ABSTRACT PUBMED 9695947

About this Structure

2FFH is a Single protein structure of sequence from Thermus aquaticus. Full crystallographic information is available from OCA.

Reference

Crystal structure of the signal sequence binding subunit of the signal recognition particle., Keenan RJ, Freymann DM, Walter P, Stroud RM, Cell. 1998 Jul 24;94(2):181-91. PMID:9695947

Page seeded by OCA on Tue Jul 29 07:29:03 2008

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