2fme
From Proteopedia
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{{STRUCTURE_2fme| PDB=2fme | SCENE= }} | {{STRUCTURE_2fme| PDB=2fme | SCENE= }} | ||
| - | + | ===Crystal structure of the mitotic kinesin eg5 (ksp) in complex with mg-adp and (r)-4-(3-hydroxyphenyl)-n,n,7,8-tetramethyl-3,4-dihydroisoquinoline-2(1h)-carboxamide=== | |
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==About this Structure== | ==About this Structure== | ||
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[[Category: Sheriff, S.]] | [[Category: Sheriff, S.]] | ||
[[Category: Eg5 ksp mg-adp complex inhibitor]] | [[Category: Eg5 ksp mg-adp complex inhibitor]] | ||
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Revision as of 14:10, 27 July 2008
Crystal structure of the mitotic kinesin eg5 (ksp) in complex with mg-adp and (r)-4-(3-hydroxyphenyl)-n,n,7,8-tetramethyl-3,4-dihydroisoquinoline-2(1h)-carboxamide
Template:ABSTRACT PUBMED 16458511
About this Structure
2FME is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Inhibitors of human mitotic kinesin Eg5: characterization of the 4-phenyl-tetrahydroisoquinoline lead series., Tarby CM, Kaltenbach RF 3rd, Huynh T, Pudzianowski A, Shen H, Ortega-Nanos M, Sheriff S, Newitt JA, McDonnell PA, Burford N, Fairchild CR, Vaccaro W, Chen Z, Borzilleri RM, Naglich J, Lombardo LJ, Gottardis M, Trainor GL, Roussell DL, Bioorg Med Chem Lett. 2006 Apr 15;16(8):2095-100. Epub 2006 Feb 3. PMID:16458511
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