2fwm

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{{STRUCTURE_2fwm| PDB=2fwm | SCENE= }}
{{STRUCTURE_2fwm| PDB=2fwm | SCENE= }}
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'''Crystal Structure of E. coli EntA, a 2,3-dihydrodihydroxy benzoate dehydrogenase'''
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===Crystal Structure of E. coli EntA, a 2,3-dihydrodihydroxy benzoate dehydrogenase===
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==Overview==
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The Escherichia coli enterobactin synthetic cluster is composed of six proteins, EntA-EntF, that form the enterobactin molecule from three serine molecules and three molecules of 2,3-dihydroxybenzoic acid (DHB). EntC, EntB and EntA catalyze the three-step synthesis of DHB from chorismate. EntA is a member of the short-chain oxidoreductase (SCOR) family of proteins and catalyzes the final step in DHB synthesis, the NAD+-dependent oxidation of 2,3-dihydro-2,3-dihydroxybenzoic acid to DHB. The structure of EntA has been determined by multi-wavelength anomalous dispersion methods. Here, the 2.0 A crystal structure of EntA in the unliganded form is presented. Analysis of the structure in light of recent structural and bioinformatic analysis of other members of the SCOR family provides insight into the residues involved in cofactor and substrate binding.
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(as it appears on PubMed at http://www.pubmed.gov), where 16790929 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16790929}}
==About this Structure==
==About this Structure==
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[[Category: Short-chain oxidoreductase]]
[[Category: Short-chain oxidoreductase]]
[[Category: Tetramer]]
[[Category: Tetramer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 04:23:31 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 23:43:37 2008''

Revision as of 20:43, 28 July 2008

Image:2fwm.png

Template:STRUCTURE 2fwm

Crystal Structure of E. coli EntA, a 2,3-dihydrodihydroxy benzoate dehydrogenase

Template:ABSTRACT PUBMED 16790929

About this Structure

2FWM is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Determination of the crystal structure of EntA, a 2,3-dihydro-2,3-dihydroxybenzoic acid dehydrogenase from Escherichia coli., Sundlov JA, Garringer JA, Carney JM, Reger AS, Drake EJ, Duax WL, Gulick AM, Acta Crystallogr D Biol Crystallogr. 2006 Jul;62(Pt 7):734-40. Epub 2006, Jun 20. PMID:16790929

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