2gcu

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{{STRUCTURE_2gcu| PDB=2gcu | SCENE= }}
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'''X-Ray Structure of Gene Product from Arabidopsis Thaliana At1g53580'''
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===X-Ray Structure of Gene Product from Arabidopsis Thaliana At1g53580===
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==Overview==
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The protein product of gene At1g53580 from Arabidopsis thaliana possesses 54% sequence identity to a human enzyme that has been implicated in the rare disorder ethylmalonic encephalopathy. The structure of the At1g53580 protein has been solved to a nominal resolution of 1.48 Angstrom. This structure reveals tertiary structure differences between the ETHE1-like enzyme and glyoxalase II enzymes that are likely to account for differences in reaction chemistry and multimeric state between the two types of enzymes. In addition, the Arabidopsis ETHE1 protein is used as a model to explain the significance of several mutations in the human enzyme that have been observed in patients with ethylmalonic encephalopathy.
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(as it appears on PubMed at http://www.pubmed.gov), where 16929096 is the PubMed ID number.
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{{ABSTRACT_PUBMED_16929096}}
==About this Structure==
==About this Structure==
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[[Category: Psi]]
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[[Category: Structural genomic]]
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Revision as of 23:36, 28 July 2008

Image:2gcu.png

Template:STRUCTURE 2gcu

X-Ray Structure of Gene Product from Arabidopsis Thaliana At1g53580

Template:ABSTRACT PUBMED 16929096

About this Structure

2GCU is a Single protein structure of sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

Structure of an ETHE1-like protein from Arabidopsis thaliana., McCoy JG, Bingman CA, Bitto E, Holdorf MM, Makaroff CA, Phillips GN Jr, Acta Crystallogr D Biol Crystallogr. 2006 Sep;62(Pt 9):964-70. Epub 2006, Aug 19. PMID:16929096

Page seeded by OCA on Tue Jul 29 02:36:17 2008

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