2gzq
From Proteopedia
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'''Phosphatidylethanolamine-binding protein from Plasmodium vivax''' | '''Phosphatidylethanolamine-binding protein from Plasmodium vivax''' | ||
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| + | ==Overview== | ||
| + | The structure of a putative Raf kinase inhibitor protein (RKIP) homolog from the eukaryotic parasite Plasmodium vivax has been studied to a resolution of 1.3 A using multiple-wavelength anomalous diffraction at the Se K edge. This protozoan protein is topologically similar to previously studied members of the phosphatidylethanolamine-binding protein (PEBP) sequence family, but exhibits a distinctive left-handed alpha-helical region at one side of the canonical phospholipid-binding site. Re-examination of previously determined PEBP structures suggests that the P. vivax protein and yeast carboxypeptidase Y inhibitor may represent a structurally distinct subfamily of the diverse PEBP-sequence family. | ||
==About this Structure== | ==About this Structure== | ||
2GZQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZQ OCA]. | 2GZQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZQ OCA]. | ||
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| + | ==Reference== | ||
| + | The structure of Plasmodium vivax phosphatidylethanolamine-binding protein suggests a functional motif containing a left-handed helix., Arakaki T, Neely H, Boni E, Mueller N, Buckner FS, Van Voorhis WC, Lauricella A, DeTitta G, Luft J, Hol WG, Merritt EA, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1;63(Pt, 3):178-82. Epub 2007 Feb 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17329808 17329808] | ||
[[Category: Plasmodium vivax]] | [[Category: Plasmodium vivax]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: Merritt, E A.]] | [[Category: Merritt, E A.]] | ||
[[Category: SGPP, Structural Genomics of Pathogenic Protozoa Consortium.]] | [[Category: SGPP, Structural Genomics of Pathogenic Protozoa Consortium.]] | ||
| + | [[Category: Lipid binding protein]] | ||
[[Category: Protein structure initiative]] | [[Category: Protein structure initiative]] | ||
[[Category: Psi]] | [[Category: Psi]] | ||
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[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
[[Category: Structural genomics of pathogenic protozoa consortium]] | [[Category: Structural genomics of pathogenic protozoa consortium]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 22 22:24:32 2008'' |
Revision as of 19:24, 22 May 2008
Phosphatidylethanolamine-binding protein from Plasmodium vivax
Overview
The structure of a putative Raf kinase inhibitor protein (RKIP) homolog from the eukaryotic parasite Plasmodium vivax has been studied to a resolution of 1.3 A using multiple-wavelength anomalous diffraction at the Se K edge. This protozoan protein is topologically similar to previously studied members of the phosphatidylethanolamine-binding protein (PEBP) sequence family, but exhibits a distinctive left-handed alpha-helical region at one side of the canonical phospholipid-binding site. Re-examination of previously determined PEBP structures suggests that the P. vivax protein and yeast carboxypeptidase Y inhibitor may represent a structurally distinct subfamily of the diverse PEBP-sequence family.
About this Structure
2GZQ is a Single protein structure of sequence from Plasmodium vivax. Full crystallographic information is available from OCA.
Reference
The structure of Plasmodium vivax phosphatidylethanolamine-binding protein suggests a functional motif containing a left-handed helix., Arakaki T, Neely H, Boni E, Mueller N, Buckner FS, Van Voorhis WC, Lauricella A, DeTitta G, Luft J, Hol WG, Merritt EA, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1;63(Pt, 3):178-82. Epub 2007 Feb 23. PMID:17329808 Page seeded by OCA on Thu May 22 22:24:32 2008
