This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2gzq
From Proteopedia
| Line 11: | Line 11: | ||
'''Phosphatidylethanolamine-binding protein from Plasmodium vivax''' | '''Phosphatidylethanolamine-binding protein from Plasmodium vivax''' | ||
| + | |||
| + | ==Overview== | ||
| + | The structure of a putative Raf kinase inhibitor protein (RKIP) homolog from the eukaryotic parasite Plasmodium vivax has been studied to a resolution of 1.3 A using multiple-wavelength anomalous diffraction at the Se K edge. This protozoan protein is topologically similar to previously studied members of the phosphatidylethanolamine-binding protein (PEBP) sequence family, but exhibits a distinctive left-handed alpha-helical region at one side of the canonical phospholipid-binding site. Re-examination of previously determined PEBP structures suggests that the P. vivax protein and yeast carboxypeptidase Y inhibitor may represent a structurally distinct subfamily of the diverse PEBP-sequence family. | ||
==About this Structure== | ==About this Structure== | ||
2GZQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZQ OCA]. | 2GZQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZQ OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | The structure of Plasmodium vivax phosphatidylethanolamine-binding protein suggests a functional motif containing a left-handed helix., Arakaki T, Neely H, Boni E, Mueller N, Buckner FS, Van Voorhis WC, Lauricella A, DeTitta G, Luft J, Hol WG, Merritt EA, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1;63(Pt, 3):178-82. Epub 2007 Feb 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17329808 17329808] | ||
[[Category: Plasmodium vivax]] | [[Category: Plasmodium vivax]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| Line 19: | Line 25: | ||
[[Category: Merritt, E A.]] | [[Category: Merritt, E A.]] | ||
[[Category: SGPP, Structural Genomics of Pathogenic Protozoa Consortium.]] | [[Category: SGPP, Structural Genomics of Pathogenic Protozoa Consortium.]] | ||
| + | [[Category: Lipid binding protein]] | ||
[[Category: Protein structure initiative]] | [[Category: Protein structure initiative]] | ||
[[Category: Psi]] | [[Category: Psi]] | ||
| Line 24: | Line 31: | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
[[Category: Structural genomics of pathogenic protozoa consortium]] | [[Category: Structural genomics of pathogenic protozoa consortium]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu May 22 22:24:32 2008'' |
Revision as of 19:24, 22 May 2008
Phosphatidylethanolamine-binding protein from Plasmodium vivax
Overview
The structure of a putative Raf kinase inhibitor protein (RKIP) homolog from the eukaryotic parasite Plasmodium vivax has been studied to a resolution of 1.3 A using multiple-wavelength anomalous diffraction at the Se K edge. This protozoan protein is topologically similar to previously studied members of the phosphatidylethanolamine-binding protein (PEBP) sequence family, but exhibits a distinctive left-handed alpha-helical region at one side of the canonical phospholipid-binding site. Re-examination of previously determined PEBP structures suggests that the P. vivax protein and yeast carboxypeptidase Y inhibitor may represent a structurally distinct subfamily of the diverse PEBP-sequence family.
About this Structure
2GZQ is a Single protein structure of sequence from Plasmodium vivax. Full crystallographic information is available from OCA.
Reference
The structure of Plasmodium vivax phosphatidylethanolamine-binding protein suggests a functional motif containing a left-handed helix., Arakaki T, Neely H, Boni E, Mueller N, Buckner FS, Van Voorhis WC, Lauricella A, DeTitta G, Luft J, Hol WG, Merritt EA, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1;63(Pt, 3):178-82. Epub 2007 Feb 23. PMID:17329808 Page seeded by OCA on Thu May 22 22:24:32 2008
