This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2hiz

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2hiz.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:2hiz.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2hiz| PDB=2hiz | SCENE= }}
{{STRUCTURE_2hiz| PDB=2hiz | SCENE= }}
-
'''Crystal Structure of human beta-secretase (BACE) in the presence of an inhibitor'''
+
===Crystal Structure of human beta-secretase (BACE) in the presence of an inhibitor===
-
==Overview==
+
<!--
-
We describe a novel series of potent inhibitors of human beta-secretase. These compounds possess the hydroxyethyl amine transition state isostere. A 2.5A crystal structure of inhibitor 32 bound to BACE is provided.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17046251}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17046251 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17046251}}
==About this Structure==
==About this Structure==
Line 29: Line 33:
[[Category: Tomasselli, A G.]]
[[Category: Tomasselli, A G.]]
[[Category: Protein-inhibitor complex]]
[[Category: Protein-inhibitor complex]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 06:21:11 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 19:23:20 2008''

Revision as of 16:23, 28 July 2008

Image:2hiz.png

Template:STRUCTURE 2hiz

Crystal Structure of human beta-secretase (BACE) in the presence of an inhibitor

Template:ABSTRACT PUBMED 17046251

About this Structure

2HIZ is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Design of potent inhibitors of human beta-secretase. Part 1., Freskos JN, Fobian YM, Benson TE, Bienkowski MJ, Brown DL, Emmons TL, Heintz R, Laborde A, McDonald JJ, Mischke BV, Molyneaux JM, Moon JB, Mullins PB, Bryan Prince D, Paddock DJ, Tomasselli AG, Winterrowd G, Bioorg Med Chem Lett. 2007 Jan 1;17(1):73-7. Epub 2006 Oct 4. PMID:17046251

Page seeded by OCA on Mon Jul 28 19:23:20 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2hiz"
Personal tools