2hm1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2hm1.gif|left|200px]]
+
{{Seed}}
 +
[[Image:2hm1.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2hm1| PDB=2hm1 | SCENE= }}
{{STRUCTURE_2hm1| PDB=2hm1 | SCENE= }}
-
'''Crystal Structure of human beta-secretase (BACE) in the presence of an inhibitor (2)'''
+
===Crystal Structure of human beta-secretase (BACE) in the presence of an inhibitor (2)===
-
==Overview==
+
<!--
-
We describe an optimized series of acyclic hydroxyethylamine transition state isosteres of beta-secretase that incorporates a variety of P(2) side chains that yield potent inhibitors with excellent cellular activity. A 2.2A crystal structure of compound 13 is shown.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17049233}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17049233 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17049233}}
==About this Structure==
==About this Structure==
Line 29: Line 33:
[[Category: Tomasselli, A G.]]
[[Category: Tomasselli, A G.]]
[[Category: Protein-inhibitor complex]]
[[Category: Protein-inhibitor complex]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 06:26:38 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 12:20:43 2008''

Revision as of 09:20, 27 July 2008

Template:STRUCTURE 2hm1

Crystal Structure of human beta-secretase (BACE) in the presence of an inhibitor (2)

Template:ABSTRACT PUBMED 17049233

About this Structure

2HM1 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Design of potent inhibitors of human beta-secretase. Part 2., Freskos JN, Fobian YM, Benson TE, Moon JB, Bienkowski MJ, Brown DL, Emmons TL, Heintz R, Laborde A, McDonald JJ, Mischke BV, Molyneaux JM, Mullins PB, Bryan Prince D, Paddock DJ, Tomasselli AG, Winterrowd G, Bioorg Med Chem Lett. 2007 Jan 1;17(1):78-81. Epub 2006 Oct 4. PMID:17049233

Page seeded by OCA on Sun Jul 27 12:20:43 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools