This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2q1b
From Proteopedia
(New page: 200px<br /> <applet load="2q1b" size="450" color="white" frame="true" align="right" spinBox="true" caption="2q1b, resolution 1.70Å" /> '''Carbonic Anhydrase ...) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:2q1b. | + | [[Image:2q1b.jpg|left|200px]]<br /><applet load="2q1b" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="2q1b" size=" | + | |
caption="2q1b, resolution 1.70Å" /> | caption="2q1b, resolution 1.70Å" /> | ||
'''Carbonic Anhydrase II in Complex with Saccharin'''<br /> | '''Carbonic Anhydrase II in Complex with Saccharin'''<br /> | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=611492 611492]] | ||
==About this Structure== | ==About this Structure== | ||
| - | 2Q1B is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with ZN, HG, BEZ and LSA as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http:// | + | 2Q1B is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=HG:'>HG</scene>, <scene name='pdbligand=BEZ:'>BEZ</scene> and <scene name='pdbligand=LSA:'>LSA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q1B OCA]. |
==Reference== | ==Reference== | ||
| Line 26: | Line 22: | ||
[[Category: twisted beta-sheet]] | [[Category: twisted beta-sheet]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 12:57:20 2008'' |
Revision as of 10:57, 23 January 2008
|
Carbonic Anhydrase II in Complex with Saccharin
About this Structure
2Q1B is a Single protein structure of sequence from Homo sapiens with , , and as ligands. Active as Carbonate dehydratase, with EC number 4.2.1.1 Full crystallographic information is available from OCA.
Reference
Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste., Kohler K, Hillebrecht A, Schulze Wischeler J, Innocenti A, Heine A, Supuran CT, Klebe G, Angew Chem Int Ed Engl. 2007;46(40):7697-9. PMID:17705204
Page seeded by OCA on Wed Jan 23 12:57:20 2008
Categories: Carbonate dehydratase | Homo sapiens | Single protein | Heine, A. | Klebe, G. | Koehler, K. | BEZ | HG | LSA | ZN | 10-stranded | Lyase | Twisted beta-sheet
