2q8k
From Proteopedia
(New page: 200px<br /> <applet load="2q8k" size="450" color="white" frame="true" align="right" spinBox="true" caption="2q8k, resolution 1.60Å" /> '''The crystal structu...) |
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caption="2q8k, resolution 1.60Å" /> | caption="2q8k, resolution 1.60Å" /> | ||
'''The crystal structure of Ebp1'''<br /> | '''The crystal structure of Ebp1'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2Q8K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with SO4 and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http:// | + | 2Q8K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q8K OCA]. |
==Reference== | ==Reference== | ||
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[[Category: transcription]] | [[Category: transcription]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 13:28:47 2008'' |
Revision as of 11:28, 23 January 2008
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The crystal structure of Ebp1
Overview
The ErbB-3 receptor binding protein (Ebp1) is a member of the, proliferation-associated 2G4 (PA2G4) family implicated in regulation of, cell growth and differentiation. Here, we report the crystal structure of, the human Ebp1 at 1.6A resolution. The protein has the conserved pita, bread fold of methionine aminopeptidases, but without the characteristic, enzymatic activity. Moreover, Ebp1 is known to interact with a number of, proteins and RNAs involved in either transcription regulation or, translation control. The structure provides insights in how Ebp1, discriminates between its different interaction partners.
About this Structure
2Q8K is a Single protein structure of sequence from Homo sapiens with and as ligands. Full crystallographic information is available from OCA.
Reference
The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions., Kowalinski E, Bange G, Bradatsch B, Hurt E, Wild K, Sinning I, FEBS Lett. 2007 Sep 18;581(23):4450-4. Epub 2007 Aug 27. PMID:17765895
Page seeded by OCA on Wed Jan 23 13:28:47 2008
Categories: Homo sapiens | Single protein | Bange, G. | Kowalinski, E. | Sinning, I. | Wild, K. | GOL | SO4 | Ebp1 | Methionine aminopeptidase | Pa2g4 | Pita-bread | Transcription
