2qcf
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="2qcf" size="450" color="white" frame="true" align="right" spinBox="true" caption="2qcf, resolution 1.22Å" /> '''Crystal structure o...) |
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| - | [[Image:2qcf. | + | [[Image:2qcf.jpg|left|200px]]<br /><applet load="2qcf" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="2qcf" size=" | + | |
caption="2qcf, resolution 1.22Å" /> | caption="2qcf, resolution 1.22Å" /> | ||
'''Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP'''<br /> | '''Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP'''<br /> | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Oroticaciduria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=258900 258900]] | ||
==About this Structure== | ==About this Structure== | ||
| - | 2QCF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with S, 5FU and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] Full crystallographic information is available from [http:// | + | 2QCF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=S:'>S</scene>, <scene name='pdbligand=5FU:'>5FU</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QCF OCA]. |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Orotidine-5'-phosphate decarboxylase]] | [[Category: Orotidine-5'-phosphate decarboxylase]] | ||
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[[Category: ump synthase]] | [[Category: ump synthase]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 12:23:00 2008'' |
Revision as of 10:23, 23 January 2008
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Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 5-fluoro-UMP
About this Structure
2QCF is a Single protein structure of sequence from Homo sapiens with , and as ligands. Active as Orotidine-5'-phosphate decarboxylase, with EC number 4.1.1.23 Full crystallographic information is available from OCA.
Page seeded by OCA on Wed Jan 23 12:23:00 2008
