2i6e

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{{STRUCTURE_2i6e| PDB=2i6e | SCENE= }}
{{STRUCTURE_2i6e| PDB=2i6e | SCENE= }}
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'''Crystal structure of protein DR0370 from Deinococcus radiodurans, Pfam DUF178'''
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===Crystal structure of protein DR0370 from Deinococcus radiodurans, Pfam DUF178===
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==Overview==
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BACKGROUND: Pfam is a comprehensive collection of protein domains and families, with a range of well-established information including genome annotation. Pfam has two large series of functionally uncharacterized families, known as Domains of Unknown Function (DUFs) and Uncharacterized Protein Families (UPFs). RESULTS: Crystal structures of two proteins from Deinococcus radiodurans and Streptomyces coelicolor belonging to Pfam protein family DUF178 (ID: PF02621) have been determined using Selenium-Single-wavelength Anomalous Dispersion (Se-SAD). Based on the structure, we have identified the putative function for this family of protein. CONCLUSION: Unexpectedly, we found that DUF178 Pfam is remarkably similar to Pfam family DUF191 suggesting that the sequence-based classification alone may not be sufficient to classify proteins into Pfam families.
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(as it appears on PubMed at http://www.pubmed.gov), where 17908300 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17908300}}
==About this Structure==
==About this Structure==
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Unknown function]]
[[Category: Unknown function]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 08:10:27 2008''

Revision as of 05:10, 29 July 2008

Image:2i6e.png

Template:STRUCTURE 2i6e

Crystal structure of protein DR0370 from Deinococcus radiodurans, Pfam DUF178

Template:ABSTRACT PUBMED 17908300

About this Structure

2I6E is a Single protein structure of sequence from Deinococcus radiodurans. Full crystallographic information is available from OCA.

Reference

X-ray structures of two proteins belonging to Pfam DUF178 revealed unexpected structural similarity to the DUF191 Pfam family., Tyagi R, Burley SK, Swaminathan S, BMC Struct Biol. 2007 Oct 1;7:62. PMID:17908300

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