2ibl

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[[Image:2ibl.jpg|left|200px]]
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{{STRUCTURE_2ibl| PDB=2ibl | SCENE= }}
{{STRUCTURE_2ibl| PDB=2ibl | SCENE= }}
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'''Crystal structure of a helper molecule (HT-mf-thromb) based on mini-fibritin (mf) crystal structure (pdb:1OX3).'''
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===Crystal structure of a helper molecule (HT-mf-thromb) based on mini-fibritin (mf) crystal structure (pdb:1OX3).===
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==Overview==
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Hantaviruses can cause hemorrhagic fever with a renal syndrome and hantavirus pulmonary syndrome when transmitted to humans. The nucleocapsid protein of hantaviruses encapsidates viral genomic RNA and associates with transcription and replication complexes. Both the amino and carboxy termini of the nucleocapsid protein had been predicted to form trimers prior to the formation of the ribonucleoprotein. Crystal structures of amino-terminal fragments of the nucleocapsid protein showed the formation of intramolecular antiparallel coiled coils, but not intermolecular trimers. Thus, the amino-terminal part of the nucleocapsid protein is probably insufficient to initiate the trimerization of the full-length molecule.
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The line below this paragraph, {{ABSTRACT_PUBMED_17222867}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 17222867 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17222867}}
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
The coiled-coil domain structure of the Sin Nombre virus nucleocapsid protein., Boudko SP, Kuhn RJ, Rossmann MG, J Mol Biol. 2007 Mar 9;366(5):1538-44. Epub 2006 Dec 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17222867 17222867]
The coiled-coil domain structure of the Sin Nombre virus nucleocapsid protein., Boudko SP, Kuhn RJ, Rossmann MG, J Mol Biol. 2007 Mar 9;366(5):1538-44. Epub 2006 Dec 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17222867 17222867]
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Design and crystal structure of bacteriophage T4 mini-fibritin NCCF., Boudko SP, Strelkov SV, Engel J, Stetefeld J, J Mol Biol. 2004 Jun 11;339(4):927-35. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15165860 15165860]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Unidentified phage]]
[[Category: Unidentified phage]]
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[[Category: Mini-fibritin]]
[[Category: Mini-fibritin]]
[[Category: Trimerization]]
[[Category: Trimerization]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 07:17:56 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:54:30 2008''

Revision as of 17:54, 27 July 2008

Image:2ibl.png

Template:STRUCTURE 2ibl

Crystal structure of a helper molecule (HT-mf-thromb) based on mini-fibritin (mf) crystal structure (pdb:1OX3).

Template:ABSTRACT PUBMED 17222867

About this Structure

2IBL is a Single protein structure of sequence from Unidentified phage. Full crystallographic information is available from OCA.

Reference

The coiled-coil domain structure of the Sin Nombre virus nucleocapsid protein., Boudko SP, Kuhn RJ, Rossmann MG, J Mol Biol. 2007 Mar 9;366(5):1538-44. Epub 2006 Dec 23. PMID:17222867

Design and crystal structure of bacteriophage T4 mini-fibritin NCCF., Boudko SP, Strelkov SV, Engel J, Stetefeld J, J Mol Biol. 2004 Jun 11;339(4):927-35. PMID:15165860

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