2irt

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2irt.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:2irt.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2irt| PDB=2irt | SCENE= }}
{{STRUCTURE_2irt| PDB=2irt | SCENE= }}
-
'''INITIAL CRYSTALLOGRAPHIC ANALYSES OF A RECOMBINANT INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN'''
+
===INITIAL CRYSTALLOGRAPHIC ANALYSES OF A RECOMBINANT INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN===
-
==Overview==
+
<!--
-
We report the crystallization of samples of a recombinant preparation of human interleukin-1 receptor antagonist protein (IRAP) and solution of the crystal structure by isomorphous replacement methods. Crystals were obtained by the hanging-drop vapor-diffusion method at 277 K from solutions of PEG 4000 containing sodium chloride, dithiothreitol and PIPES [sodium piperazione-N,N'-bis(2-ethanesulfonate)] buffer at pH 7.0. Crystals appear within about a week and grow as truncated tetragonal bipyramids to 0.3-0.6 mm on an edge. X-ray diffraction data from these crystals specify space group P4(3)2(1)2 and unit-cell dimensions of a = b = 72.35(26), c = 114.7(8) A and Z = 16 (two molecules per asymmetric unit). Fresh crystals diffract to about 2.3 A resolution. The search for heavy-atom derivatives has produced two, potassium gold cyanide and trimethyl lead chloride, as same-site, single-site derivatives. Inspection of an electron-density map at 4 A resolution calculated with these derivatives confirms that the IRAP molecule is a member of the interleukin-1 structural family.
+
The line below this paragraph, {{ABSTRACT_PUBMED_15299459}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 15299459 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_15299459}}
==About this Structure==
==About this Structure==
Line 26: Line 30:
[[Category: Finzel, B C.]]
[[Category: Finzel, B C.]]
[[Category: Signal protein]]
[[Category: Signal protein]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 07:47:21 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 23:56:51 2008''

Revision as of 20:56, 28 July 2008

Template:STRUCTURE 2irt

INITIAL CRYSTALLOGRAPHIC ANALYSES OF A RECOMBINANT INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN

Template:ABSTRACT PUBMED 15299459

About this Structure

2IRT is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Initial crystallographic analysis of a recombinant human interleukin-1 receptor antagonist protein., Clancy LL, Finzel BC, Yem AW, Deibel MR Jr, Strakalaitis NA, Brunner DP, Sweet RM, Einspahr HM, Acta Crystallogr D Biol Crystallogr. 1994 Mar 1;50(Pt 2):197-201. PMID:15299459

Page seeded by OCA on Mon Jul 28 23:56:51 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools