2uwl
From Proteopedia
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| - | [[Image:2uwl.gif|left|200px]]<br /> | + | [[Image:2uwl.gif|left|200px]]<br /><applet load="2uwl" size="450" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="2uwl" size="450" color="white" frame="true" align="right" spinBox="true" | + | |
caption="2uwl, resolution 1.90Å" /> | caption="2uwl, resolution 1.90Å" /> | ||
'''SELECTIVE AND DUAL ACTION ORALLY ACTIVE INHIBITORS OF THROMBIN AND FACTOR XA'''<br /> | '''SELECTIVE AND DUAL ACTION ORALLY ACTIVE INHIBITORS OF THROMBIN AND FACTOR XA'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2UWL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with 895 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_Xa Coagulation factor Xa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.6 3.4.21.6] | + | 2UWL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with 895 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_Xa Coagulation factor Xa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.6 3.4.21.6] Known structural/functional Site: <scene name='pdbsite=AC1:895 Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2UWL OCA]. |
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: zymogen]] | [[Category: zymogen]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 20:19:02 2007'' |
Revision as of 18:09, 18 December 2007
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SELECTIVE AND DUAL ACTION ORALLY ACTIVE INHIBITORS OF THROMBIN AND FACTOR XA
Disease
Known disease associated with this structure: Factor X deficiency OMIM:[227600]
About this Structure
2UWL is a Single protein structure of sequence from Homo sapiens with 895 as ligand. Active as Coagulation factor Xa, with EC number 3.4.21.6 Known structural/functional Site: . Full crystallographic information is available from OCA.
Page seeded by OCA on Tue Dec 18 20:19:02 2007
Categories: Coagulation factor Xa | Homo sapiens | Single protein | Brown, D. | Burns-Kurtis, C.L. | Chan, C. | Convery, M.A. | Hubbard, J.A. | Kelly, H.A. | Pateman, A.J. | Patikis, A. | Senger, S. | Shah, G.P. | Toomey, J.R. | Watson, N.S. | Young, R.J. | Zhou, P. | 895 | Blood coagulation | Calcium | Cleavage on pair of basic residues | Complex | Egf-like domain | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydroxylation | Polymorphism | Protease | Serine protease | Target hopping | Zymogen
