This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2ius

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2ius.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:2ius.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2ius| PDB=2ius | SCENE= }}
{{STRUCTURE_2ius| PDB=2ius | SCENE= }}
-
'''E. COLI FTSK MOTOR DOMAIN'''
+
===E. COLI FTSK MOTOR DOMAIN===
-
==Overview==
+
<!--
-
FtsK is a DNA translocase that coordinates chromosome segregation and cell division in bacteria. In addition to its role as activator of XerCD site-specific recombination, FtsK can translocate double-stranded DNA (dsDNA) rapidly and directionally and reverse direction. We present crystal structures of the FtsK motor domain monomer, showing that it has a RecA-like core, the FtsK hexamer, and also showing that it is a ring with a large central annulus and a dodecamer consisting of two hexamers, head to head. Electron microscopy (EM) demonstrates the DNA-dependent existence of hexamers in solution and shows that duplex DNA passes through the middle of each ring. Comparison of FtsK monomer structures from two different crystal forms highlights a conformational change that we propose is the structural basis for a rotary inchworm mechanism of DNA translocation.
+
The line below this paragraph, {{ABSTRACT_PUBMED_16916635}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 16916635 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_16916635}}
==About this Structure==
==About this Structure==
Line 42: Line 46:
[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 07:54:39 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 10:06:37 2008''

Revision as of 07:06, 28 July 2008

Image:2ius.png

Template:STRUCTURE 2ius

E. COLI FTSK MOTOR DOMAIN

Template:ABSTRACT PUBMED 16916635

About this Structure

2IUS is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Double-stranded DNA translocation: structure and mechanism of hexameric FtsK., Massey TH, Mercogliano CP, Yates J, Sherratt DJ, Lowe J, Mol Cell. 2006 Aug;23(4):457-69. PMID:16916635

Page seeded by OCA on Mon Jul 28 10:06:37 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ius"
Personal tools