2msp

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[[Image:2msp.gif|left|200px]]
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{{Seed}}
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[[Image:2msp.png|left|200px]]
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{{STRUCTURE_2msp| PDB=2msp | SCENE= }}
{{STRUCTURE_2msp| PDB=2msp | SCENE= }}
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'''MAJOR SPERM PROTEIN, BETA ISOFORM, ENGINEERED C59S/T90C MUTANT, PUTATIVE SUBFILAMENT STRUCTURE, PH 8.5'''
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===MAJOR SPERM PROTEIN, BETA ISOFORM, ENGINEERED C59S/T90C MUTANT, PUTATIVE SUBFILAMENT STRUCTURE, PH 8.5===
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==Overview==
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Cell locomotion in amoeboid nematode sperm is generated by the vectorial assembly and bundling of filaments of the major sperm protein (MSP). MSP filaments are constructed from two helical subfilaments and here we describe the structure of putative MSP subfilament helices determined by X-ray crystallography at 3.3 A resolution. In addition to establishing the interfaces involved in polymerization, this structural model shows that the MSP helices are constructed from dimers and have no overall polarity, suggesting that it is unlikely that molecular motors play a direct role in the generation of protrusive force in these amoeboid cells.
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The line below this paragraph, {{ABSTRACT_PUBMED_9501910}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 9501910 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9501910}}
==About this Structure==
==About this Structure==
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[[Category: Filamentous protein structure]]
[[Category: Filamentous protein structure]]
[[Category: Nematode sperm cell motility protein]]
[[Category: Nematode sperm cell motility protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 09:34:46 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:10:53 2008''

Revision as of 10:10, 29 July 2008

Image:2msp.png

Template:STRUCTURE 2msp

MAJOR SPERM PROTEIN, BETA ISOFORM, ENGINEERED C59S/T90C MUTANT, PUTATIVE SUBFILAMENT STRUCTURE, PH 8.5

Template:ABSTRACT PUBMED 9501910

About this Structure

2MSP is a Single protein structure of sequence from Ascaris suum. Full crystallographic information is available from OCA.

Reference

Structural basis for amoeboid motility in nematode sperm., Bullock TL, McCoy AJ, Kent HM, Roberts TM, Stewart M, Nat Struct Biol. 1998 Mar;5(3):184-9. PMID:9501910

Page seeded by OCA on Tue Jul 29 13:10:53 2008

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