2nvg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2nvg.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:2nvg.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2nvg| PDB=2nvg | SCENE= }}
{{STRUCTURE_2nvg| PDB=2nvg | SCENE= }}
-
'''Soluble domain of Rieske Iron Sulfur protein.'''
+
===Soluble domain of Rieske Iron Sulfur protein.===
-
==Overview==
+
<!--
-
The Rieske [2Fe-2S] iron-sulfur protein of cytochrome bc(1) functions as the initial electron acceptor in the rate-limiting step of the catalytic reaction. Prior studies have established roles for a number of conserved residues that hydrogen bond to ligands of the [2Fe-2S] cluster. We have constructed site-specific variants at two of these residues, measured their thermodynamic and functional properties, and determined atomic resolution X-ray crystal structures for the native protein at 1.2 A resolution and for five variants (Ser-154--&gt;Ala, Ser-154--&gt;Thr, Ser-154--&gt;Cys, Tyr-156--&gt;Phe, and Tyr-156--&gt;Trp) to resolutions between 1.5 A and 1.1 A. These structures and complementary biophysical data provide a molecular framework for understanding the role hydrogen bonds to the cluster play in tuning thermodynamic properties, and hence the rate of this bioenergetic reaction. These studies provide a detailed structure-function dissection of the role of hydrogen bonds in tuning the redox potentials of [2Fe-2S] clusters.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17223530}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17223530 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17223530}}
==About this Structure==
==About this Structure==
Line 28: Line 32:
[[Category: Lhee, S.]]
[[Category: Lhee, S.]]
[[Category: Nair, S K.]]
[[Category: Nair, S K.]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 09:57:33 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 13:52:25 2008''

Revision as of 10:52, 27 July 2008

Image:2nvg.png

Template:STRUCTURE 2nvg

Soluble domain of Rieske Iron Sulfur protein.

Template:ABSTRACT PUBMED 17223530

About this Structure

2NVG is a Single protein structure of sequence from Rhodobacter sphaeroides. Full crystallographic information is available from OCA.

Reference

Atomic resolution structures of rieske iron-sulfur protein: role of hydrogen bonds in tuning the redox potential of iron-sulfur clusters., Kolling DJ, Brunzelle JS, Lhee S, Crofts AR, Nair SK, Structure. 2007 Jan;15(1):29-38. PMID:17223530

Page seeded by OCA on Sun Jul 27 13:52:25 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2nvg"
Personal tools