2o07

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2o07.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:2o07.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2o07| PDB=2o07 | SCENE= }}
{{STRUCTURE_2o07| PDB=2o07 | SCENE= }}
-
'''Human spermidine synthase'''
+
===Human spermidine synthase===
-
==Overview==
+
<!--
-
Aminopropyltransferases transfer aminopropyl groups from decarboxylated S-adenosylmethionine to amine acceptors, forming polyamines. Structural and biochemical studies have been carried out with the human spermidine synthase, which is highly specific for putrescine as the amine acceptor, and the Thermotoga maritima spermidine synthase, which prefers putrescine but is more tolerant of other substrates. Comparison of the structures of the human spermidine synthase with both substrates and products with the known structure of T. maritima spermidine synthase complexed to a multisubstrate analogue inhibitor and analysis of the properties of site-directed mutants provide a general mechanistic hypothesis for the aminopropyl transfer reaction. The studies also provide a structural basis for the specificity of the spermidine synthase subclass of the aminopropyltransferase family.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17585781}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17585781 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17585781}}
==About this Structure==
==About this Structure==
Line 38: Line 42:
[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
[[Category: Structural genomics consortium]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 10:08:33 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat Jul 5 16:24:52 2008''

Revision as of 13:24, 5 July 2008

Image:2o07.png

Template:STRUCTURE 2o07

Human spermidine synthase

Template:ABSTRACT PUBMED 17585781

About this Structure

2O07 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Structure and mechanism of spermidine synthases., Wu H, Min J, Ikeguchi Y, Zeng H, Dong A, Loppnau P, Pegg AE, Plotnikov AN, Biochemistry. 2007 Jul 17;46(28):8331-9. Epub 2007 Jun 22. PMID:17585781

Page seeded by OCA on Sat Jul 5 16:24:52 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2o07"
Personal tools