2of4
From Proteopedia
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{{STRUCTURE_2of4| PDB=2of4 | SCENE= }} | {{STRUCTURE_2of4| PDB=2of4 | SCENE= }} | ||
| - | + | ===crystal structure of furanopyrimidine 1 bound to lck=== | |
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==Disease== | ==Disease== | ||
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[[Category: Kinase domain]] | [[Category: Kinase domain]] | ||
[[Category: Lck]] | [[Category: Lck]] | ||
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Revision as of 09:08, 29 July 2008
Contents |
crystal structure of furanopyrimidine 1 bound to lck
Template:ABSTRACT PUBMED 17276681
Disease
Known disease associated with this structure: SCID due to LCK deficiency OMIM:[153390]
About this Structure
2OF4 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic properties., Martin MW, Newcomb J, Nunes JJ, Bemis JE, McGowan DC, White RD, Buchanan JL, DiMauro EF, Boucher C, Faust T, Hsieh F, Huang X, Lee JH, Schneider S, Turci SM, Zhu X, Bioorg Med Chem Lett. 2007 Apr 15;17(8):2299-304. Epub 2007 Jan 24. PMID:17276681
Page seeded by OCA on Tue Jul 29 12:08:11 2008
