1s5l
From Proteopedia
(New page: 200px<br /> <applet load="1s5l" size="450" color="white" frame="true" align="right" spinBox="true" caption="1s5l, resolution 3.5Å" /> '''Architecture of the ...) |
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| - | [[Image:1s5l.gif|left|200px]]<br /> | + | [[Image:1s5l.gif|left|200px]]<br /><applet load="1s5l" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="1s5l" size=" | + | |
caption="1s5l, resolution 3.5Å" /> | caption="1s5l, resolution 3.5Å" /> | ||
'''Architecture of the photosynthetic oxygen evolving center'''<br /> | '''Architecture of the photosynthetic oxygen evolving center'''<br /> | ||
==Overview== | ==Overview== | ||
| - | Photosynthesis uses light energy to drive the oxidation of water at an | + | Photosynthesis uses light energy to drive the oxidation of water at an oxygen-evolving catalytic site within photosystem II (PSII). We report the structure of PSII of the cyanobacterium Thermosynechococcus elongatus at 3.5 angstrom resolution. We have assigned most of the amino acid residues of this 650-kilodalton dimeric multisubunit complex and refined the structure to reveal its molecular architecture. Consequently, we are able to describe details of the binding sites for cofactors and propose a structure of the oxygen-evolving center (OEC). The data strongly suggest that the OEC contains a cubane-like Mn3CaO4 cluster linked to a fourth Mn by a mono-micro-oxo bridge. The details of the surrounding coordination sphere of the metal cluster and the implications for a possible oxygen-evolving mechanism are discussed. |
==About this Structure== | ==About this Structure== | ||
| - | 1S5L is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermosynechococcus_elongatus Thermosynechococcus elongatus] with FE, BCT, OEC, CL1, PHO, HEM, PL9, LMT and BCR as [http://en.wikipedia.org/wiki/ligands ligands]. The following page contains interesting information on the relation of 1S5L with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb59_1.html Photosystem II]]. Full crystallographic information is available from [http:// | + | 1S5L is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermosynechococcus_elongatus Thermosynechococcus elongatus] with <scene name='pdbligand=FE:'>FE</scene>, <scene name='pdbligand=BCT:'>BCT</scene>, <scene name='pdbligand=OEC:'>OEC</scene>, <scene name='pdbligand=CL1:'>CL1</scene>, <scene name='pdbligand=PHO:'>PHO</scene>, <scene name='pdbligand=HEM:'>HEM</scene>, <scene name='pdbligand=PL9:'>PL9</scene>, <scene name='pdbligand=LMT:'>LMT</scene> and <scene name='pdbligand=BCR:'>BCR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. The following page contains interesting information on the relation of 1S5L with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb59_1.html Photosystem II]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S5L OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Thermosynechococcus elongatus]] | [[Category: Thermosynechococcus elongatus]] | ||
[[Category: Barber, J.]] | [[Category: Barber, J.]] | ||
| - | [[Category: Ferreira, K | + | [[Category: Ferreira, K N.]] |
| - | [[Category: Iverson, T | + | [[Category: Iverson, T M.]] |
[[Category: Iwata, S.]] | [[Category: Iwata, S.]] | ||
[[Category: Maghlaoui, K.]] | [[Category: Maghlaoui, K.]] | ||
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[[Category: tetra-manganese]] | [[Category: tetra-manganese]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:58:11 2008'' |
Revision as of 12:58, 21 February 2008
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Architecture of the photosynthetic oxygen evolving center
Overview
Photosynthesis uses light energy to drive the oxidation of water at an oxygen-evolving catalytic site within photosystem II (PSII). We report the structure of PSII of the cyanobacterium Thermosynechococcus elongatus at 3.5 angstrom resolution. We have assigned most of the amino acid residues of this 650-kilodalton dimeric multisubunit complex and refined the structure to reveal its molecular architecture. Consequently, we are able to describe details of the binding sites for cofactors and propose a structure of the oxygen-evolving center (OEC). The data strongly suggest that the OEC contains a cubane-like Mn3CaO4 cluster linked to a fourth Mn by a mono-micro-oxo bridge. The details of the surrounding coordination sphere of the metal cluster and the implications for a possible oxygen-evolving mechanism are discussed.
About this Structure
1S5L is a Protein complex structure of sequences from Thermosynechococcus elongatus with , , , , , , , and as ligands. The following page contains interesting information on the relation of 1S5L with [Photosystem II]. Full crystallographic information is available from OCA.
Reference
Architecture of the photosynthetic oxygen-evolving center., Ferreira KN, Iverson TM, Maghlaoui K, Barber J, Iwata S, Science. 2004 Mar 19;303(5665):1831-8. Epub 2004 Feb 5. PMID:14764885
Page seeded by OCA on Thu Feb 21 14:58:11 2008
Categories: Photosystem II | Protein complex | Thermosynechococcus elongatus | Barber, J. | Ferreira, K N. | Iverson, T M. | Iwata, S. | Maghlaoui, K. | BCR | BCT | CL1 | FE | HEM | LMT | OEC | PHO | PL9 | Membrane | Oxygen-evolving | Photosynthesis | Photosystem | Tetra-manganese
