This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2otg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2otg.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:2otg.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2otg| PDB=2otg | SCENE= }}
{{STRUCTURE_2otg| PDB=2otg | SCENE= }}
-
'''Rigor-like structures of muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor'''
+
===Rigor-like structures of muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor===
-
==Overview==
+
<!--
-
Unlike processive cellular motors such as myosin V, whose structure has recently been determined in a "rigor-like" conformation, myosin II from contracting muscle filaments necessarily spends most of its time detached from actin. By using squid and sea scallop sources, however, we have now obtained similar rigor-like atomic structures for muscle myosin heads (S1). The significance of the hallmark closed actin-binding cleft in these crystal structures is supported here by actin/S1-binding studies. These structures reveal how different duty ratios, and hence cellular functions, of the myosin isoforms may be accounted for, in part, on the basis of detailed differences in interdomain contacts. Moreover, the rigor-like position of switch II turns out to be unique for myosin V. The overall arrangements of subdomains in the motor are relatively conserved in each of the known contractile states, and we explore qualitatively the energetics of these states.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17502101}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17502101 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17502101}}
==About this Structure==
==About this Structure==
Line 36: Line 40:
[[Category: Myosin s1]]
[[Category: Myosin s1]]
[[Category: Rigor-like]]
[[Category: Rigor-like]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 11:37:34 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 21:09:03 2008''

Revision as of 18:09, 28 July 2008

Image:2otg.png

Template:STRUCTURE 2otg

Rigor-like structures of muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor

Template:ABSTRACT PUBMED 17502101

About this Structure

2OTG is a Protein complex structure of sequences from Placopecten magellanicus. Full crystallographic information is available from OCA.

Reference

Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor., Yang Y, Gourinath S, Kovacs M, Nyitray L, Reutzel R, Himmel DM, O'Neall-Hennessey E, Reshetnikova L, Szent-Gyorgyi AG, Brown JH, Cohen C, Structure. 2007 May;15(5):553-64. PMID:17502101

Page seeded by OCA on Mon Jul 28 21:09:03 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2otg"
Personal tools