2ott

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2ott.gif|left|200px]]
+
{{Seed}}
 +
[[Image:2ott.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2ott| PDB=2ott | SCENE= }}
{{STRUCTURE_2ott| PDB=2ott | SCENE= }}
-
'''Crystal structure of CD5_DIII'''
+
===Crystal structure of CD5_DIII===
-
==Overview==
+
<!--
-
Scavenger receptor cysteine-rich (SRCR) domains are ancient protein modules widely found among cell surface and secreted proteins of the innate and adaptive immune system, where they mediate ligand binding. We have solved the crystal structure at 2.2 A of resolution of the SRCR CD5 domain III, a human lymphocyte receptor involved in the modulation of antigen specific receptor-mediated T cell activation and differentiation signals. The first structure of a member of a group B SRCR domain reveals the fold of this ancient protein module into a central core formed by two antiparallel beta-sheets and one alpha-helix, illustrating the conserved core at the protein level of genes coding for group A and B members of the SRCR superfamily. The novel SRCR group B structure permits the interpretation of site-directed mutagenesis data on the binding of activated leukocyte cell adhesion molecule (ALCAM/CD166) binding to CD6, a closely related lymphocyte receptor homologue to CD5.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17322294}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17322294 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17322294}}
==About this Structure==
==About this Structure==
Line 24: Line 28:
[[Category: Rodamilans, B.]]
[[Category: Rodamilans, B.]]
[[Category: Srcr group b domain]]
[[Category: Srcr group b domain]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 11:38:31 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:52:38 2008''

Revision as of 09:52, 29 July 2008

Image:2ott.png

Template:STRUCTURE 2ott

Crystal structure of CD5_DIII

Template:ABSTRACT PUBMED 17322294

About this Structure

2OTT is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of the third extracellular domain of CD5 reveals the fold of a group B scavenger cysteine-rich receptor domain., Rodamilans B, Munoz IG, Bragado-Nilsson E, Sarrias MR, Padilla O, Blanco FJ, Lozano F, Montoya G, J Biol Chem. 2007 Apr 27;282(17):12669-77. Epub 2007 Feb 23. PMID:17322294

Page seeded by OCA on Tue Jul 29 12:52:38 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ott"
Personal tools