2pob

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2pob.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:2pob.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_2pob| PDB=2pob | SCENE= }}
{{STRUCTURE_2pob| PDB=2pob | SCENE= }}
-
'''PPARgamma Ligand binding domain complexed with a farglitazar analogue gw4709'''
+
===PPARgamma Ligand binding domain complexed with a farglitazar analogue gw4709===
-
==Overview==
+
<!--
-
PPARgamma-activating thiazolidinediones and carboxylic acids such as farglitazar exert their anti-diabetic effects in part in PPARgamma rich adipose. Both pro- and anti-adipogenic PPARgamma ligands promote glucose and lipid lowering in animal models of diabetes. Herein, we disclose representatives of an array of 160 farglitazar analogues with atypical inverse agonism of PPARgamma in mature adipocytes.
+
The line below this paragraph, {{ABSTRACT_PUBMED_17533125}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 17533125 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_17533125}}
==About this Structure==
==About this Structure==
Line 26: Line 30:
[[Category: Nuclear receptor,ppar]]
[[Category: Nuclear receptor,ppar]]
[[Category: Pparg]]
[[Category: Pparg]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 13:31:47 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 19:07:38 2008''

Revision as of 16:07, 27 July 2008

Image:2pob.png

Template:STRUCTURE 2pob

PPARgamma Ligand binding domain complexed with a farglitazar analogue gw4709

Template:ABSTRACT PUBMED 17533125

About this Structure

2POB is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Co-crystal structure guided array synthesis of PPARgamma inverse agonists., Trump RP, Cobb JE, Shearer BG, Lambert MH, Nolte RT, Willson TM, Buckholz RG, Zhao SM, Leesnitzer LM, Iannone MA, Pearce KH, Billin AN, Hoekstra WJ, Bioorg Med Chem Lett. 2007 Jul 15;17(14):3916-20. Epub 2007 May 18. PMID:17533125

Page seeded by OCA on Sun Jul 27 19:07:38 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2pob"
Personal tools