351d

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[[Image:351d.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_351d| PDB=351d | SCENE= }}
{{STRUCTURE_351d| PDB=351d | SCENE= }}
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'''X-RAY CRYSTAL STRUCTURES OF THE HEXAMER DCACGCG: CRYSTALS GROWN IN THE PRESENCE OF RUTHENIUM (II) HEXAMMINE CHLORIDE'''
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===X-RAY CRYSTAL STRUCTURES OF THE HEXAMER DCACGCG: CRYSTALS GROWN IN THE PRESENCE OF RUTHENIUM (II) HEXAMMINE CHLORIDE===
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==Overview==
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Hexammine ions are strong inducers of the transition from the B-form to the left-handed Z-form in DNA. Here the structure of d(CACGCG). d(CGCGTG) obtained from crystals grown from a drop containing [Ru(NH3)6]Cl3 is reported. The structure is clearly characterized as Z-DNA. When compared with the structure of d(CACGCG).d(CGCGTG)/MgCl2 and that of d(CGCGCG)2, subtle differences are seen, most noticeably in the water structure. Since stable well diffracting crystals grow easily in the presence of [Ru(NH3)6]Cl3 and since this ion is not visible in the electron density it is concluded that the ion plays a non-specific role in stabilizing Z-DNA.
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The line below this paragraph, {{ABSTRACT_PUBMED_9761846}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 9761846 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9761846}}
==About this Structure==
==About this Structure==
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[[Category: Double helix]]
[[Category: Double helix]]
[[Category: Z-dna]]
[[Category: Z-dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 20:16:49 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:26:21 2008''

Revision as of 13:26, 28 July 2008

Template:STRUCTURE 351d

X-RAY CRYSTAL STRUCTURES OF THE HEXAMER DCACGCG: CRYSTALS GROWN IN THE PRESENCE OF RUTHENIUM (II) HEXAMMINE CHLORIDE

Template:ABSTRACT PUBMED 9761846

About this Structure

Full crystallographic information is available from OCA.

Reference

Structure of d(CACGCG).d(CGCGTG) in crystals grown in the presence of ruthenium III hexammine chloride., Karthe P, Gautham N, Acta Crystallogr D Biol Crystallogr. 1998 Jul 1;54(Pt 4):501-9. PMID:9761846

Page seeded by OCA on Mon Jul 28 16:26:21 2008

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