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353d

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[[Image:353d.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_353d| PDB=353d | SCENE= }}
{{STRUCTURE_353d| PDB=353d | SCENE= }}
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'''CRYSTAL STRUCTURE OF DOMAIN A OF THERMUS FLAVUS 5S RRNA AND THE CONTRIBUTION OF WATER MOLECULES TO ITS STRUCTURE'''
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===CRYSTAL STRUCTURE OF DOMAIN A OF THERMUS FLAVUS 5S RRNA AND THE CONTRIBUTION OF WATER MOLECULES TO ITS STRUCTURE===
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==Overview==
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This is the first high resolution crystal structure of an RNA molecule made by solid phase chemical synthesis and representing a natural RNA. The structure of the domain A of Thermus flavus ribosomal 5S RNA is refined to R = 18% at 2.4 A including 159 solvent molecules. Most of the 2'-hydroxyl groups as well as the phosphate oxygens are involved either in specific hydrogen bonds in intermolecular contacts or to solvent molecules. The two U-G and G-U base-pairs are stabilized by H-bonds supplied via three water molecules to compensate for the lack of base-pair hydrogen bonds. The structure shows for the first time in detail the importance of highly ordered internal water in stabilizing an RNA structure.
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The line below this paragraph, {{ABSTRACT_PUBMED_8082756}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8082756 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8082756}}
==About this Structure==
==About this Structure==
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[[Category: A-rna]]
[[Category: A-rna]]
[[Category: Double strand]]
[[Category: Double strand]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 20:16:53 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 00:28:05 2008''

Revision as of 21:28, 28 July 2008

Image:353d.png

Template:STRUCTURE 353d

CRYSTAL STRUCTURE OF DOMAIN A OF THERMUS FLAVUS 5S RRNA AND THE CONTRIBUTION OF WATER MOLECULES TO ITS STRUCTURE

Template:ABSTRACT PUBMED 8082756

About this Structure

Full crystallographic information is available from OCA.

Reference

Crystal structure of domain A of Thermus flavus 5S rRNA and the contribution of water molecules to its structure., Betzel C, Lorenz S, Furste JP, Bald R, Zhang M, Schneider TR, Wilson KS, Erdmann VA, FEBS Lett. 1994 Sep 5;351(2):159-64. PMID:8082756

Page seeded by OCA on Tue Jul 29 00:28:05 2008

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