3bue

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{{STRUCTURE_3bue| PDB=3bue | SCENE= }}
{{STRUCTURE_3bue| PDB=3bue | SCENE= }}
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'''Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis'''
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===Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis===
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==Overview==
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The gene product of an open reading frame Rv1657 from Mycobacterium tuberculosis is a putative arginine repressor protein (ArgR), a transcriptional factor that regulates the expression of arginine-biosynthetic enzymes. Rv1657 was expressed and purified and a C-terminal domain was crystallized using the hanging-drop vapour-diffusion method. Diffraction data were collected and processed to a resolution of 2.15 A. The crystals belong to space group P1 and the Matthews coefficient suggests that the crystals contain six C-terminal domain molecules per unit cell. Previous structural and biochemical studies on the arginine repressor proteins from other organisms have likewise shown the presence of six molecules per unit cell.
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(as it appears on PubMed at http://www.pubmed.gov), where 18703843 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18703843}}
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis., Cherney LT, Cherney MM, Garen CR, Lu GJ, James MN, Acta Crystallogr D Biol Crystallogr. 2008 Sep;64(Pt 9):950-6. Epub 2008, Aug 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18703843 18703843]
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Expression, purification and preliminary X-ray analysis of the C-terminal domain of an arginine repressor protein from Mycobacterium tuberculosis., Lu GJ, Garen CR, Cherney MM, Cherney LT, Lee C, James MN, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Nov 1;63(Pt, 11):936-9. Epub 2007 Oct 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18007044 18007044]
Expression, purification and preliminary X-ray analysis of the C-terminal domain of an arginine repressor protein from Mycobacterium tuberculosis., Lu GJ, Garen CR, Cherney MM, Cherney LT, Lee C, James MN, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Nov 1;63(Pt, 11):936-9. Epub 2007 Oct 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18007044 18007044]
[[Category: Mycobacterium tuberculosis h37rv]]
[[Category: Mycobacterium tuberculosis h37rv]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 3 10:33:48 2008''

Revision as of 07:33, 3 September 2008

Image:3bue.png

Template:STRUCTURE 3bue

Crystal structure of the C-terminal domain hexamer of ArgR from Mycobacterium tuberculosis

Template:ABSTRACT PUBMED 18703843

About this Structure

3BUE is a Single protein structure of sequence from Mycobacterium tuberculosis h37rv. Full crystallographic information is available from OCA.

Reference

Structure of the C-terminal domain of the arginine repressor protein from Mycobacterium tuberculosis., Cherney LT, Cherney MM, Garen CR, Lu GJ, James MN, Acta Crystallogr D Biol Crystallogr. 2008 Sep;64(Pt 9):950-6. Epub 2008, Aug 13. PMID:18703843

Expression, purification and preliminary X-ray analysis of the C-terminal domain of an arginine repressor protein from Mycobacterium tuberculosis., Lu GJ, Garen CR, Cherney MM, Cherney LT, Lee C, James MN, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Nov 1;63(Pt, 11):936-9. Epub 2007 Oct 24. PMID:18007044

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