3cam
From Proteopedia
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'''Crystal structure of the cold shock domain protein from Neisseria meningitidis''' | '''Crystal structure of the cold shock domain protein from Neisseria meningitidis''' | ||
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| + | ==Overview== | ||
| + | The structure of the cold-shock domain protein from Neisseria meningitidis has been solved to 2.6 A resolution and shown to comprise a dimer formed by the exchange of two beta-strands between protein monomers. The overall fold of the monomer closely resembles those of other bacterial cold-shock proteins. The neisserial protein behaved as a monomer in solution and was shown to bind to a hexathymidine oligonucleotide with a stoichiometry of 1:1 and a K(d) of 1.25 microM. | ||
==About this Structure== | ==About this Structure== | ||
3CAM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_mc58 Neisseria meningitidis mc58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CAM OCA]. | 3CAM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_mc58 Neisseria meningitidis mc58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CAM OCA]. | ||
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| + | ==Reference== | ||
| + | Structure of the cold-shock domain protein from Neisseria meningitidis reveals a strand-exchanged dimer., Ren J, Nettleship JE, Sainsbury S, Saunders NJ, Owens RJ, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Apr 1;64(Pt, 4):247-51. Epub 2008 Mar 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18391418 18391418] | ||
[[Category: Neisseria meningitidis mc58]] | [[Category: Neisseria meningitidis mc58]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: Oxford protein production facility]] | [[Category: Oxford protein production facility]] | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 7 09:00:01 2008'' |
Revision as of 06:00, 7 May 2008
Crystal structure of the cold shock domain protein from Neisseria meningitidis
Overview
The structure of the cold-shock domain protein from Neisseria meningitidis has been solved to 2.6 A resolution and shown to comprise a dimer formed by the exchange of two beta-strands between protein monomers. The overall fold of the monomer closely resembles those of other bacterial cold-shock proteins. The neisserial protein behaved as a monomer in solution and was shown to bind to a hexathymidine oligonucleotide with a stoichiometry of 1:1 and a K(d) of 1.25 microM.
About this Structure
3CAM is a Single protein structure of sequence from Neisseria meningitidis mc58. Full crystallographic information is available from OCA.
Reference
Structure of the cold-shock domain protein from Neisseria meningitidis reveals a strand-exchanged dimer., Ren J, Nettleship JE, Sainsbury S, Saunders NJ, Owens RJ, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Apr 1;64(Pt, 4):247-51. Epub 2008 Mar 21. PMID:18391418 Page seeded by OCA on Wed May 7 09:00:01 2008
