4cha

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:4cha.gif|left|200px]]
+
{{Seed}}
 +
[[Image:4cha.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_4cha| PDB=4cha | SCENE= }}
{{STRUCTURE_4cha| PDB=4cha | SCENE= }}
-
'''STRUCTURE OF ALPHA-*CHYMOTRYPSIN REFINED AT 1.68 ANGSTROMS RESOLUTION'''
+
===STRUCTURE OF ALPHA-*CHYMOTRYPSIN REFINED AT 1.68 ANGSTROMS RESOLUTION===
-
==Overview==
+
<!--
-
Diffraction data for alpha-chymotrypsin crystals at -10 degrees C were measured at 1.68 A resolution and refined by restrained structure-factor least-squares refinement. The two independent chymotrypsin molecules in the crystallographic asymmetric unit were refined independently. The overall structure of alpha-chymotrypsin is little changed from published co-ordinates. The root-mean-square shift of C alpha co-ordinates is 0.42 A, co-ordinates for the two molecules showing a root-mean-square difference of 0.19 A. Certain regions with high disorder (residues 9 to 14, 73 to 79) remain difficult to interpret and several side-chains are disordered. Some water molecule positions have been changed. The absence of the tosyl group has made a significant difference to the refined structure at the active site. This now agrees closely with other enzymes of the trypsin family that have been refined at high resolution. There is a strong hydrogen bond between N epsilon 2 (His57) and O gamma (Ser195) in the free enzyme, in line with the published description of the charge relay system.
+
The line below this paragraph, {{ABSTRACT_PUBMED_4046030}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 4046030 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_4046030}}
==About this Structure==
==About this Structure==
Line 25: Line 29:
[[Category: Blow, D M.]]
[[Category: Blow, D M.]]
[[Category: Tsukada, H.]]
[[Category: Tsukada, H.]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 22:22:07 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 13:32:09 2008''

Revision as of 10:32, 3 July 2008

Image:4cha.png


PDB ID 4cha

Drag the structure with the mouse to rotate
4cha, resolution 1.68Å ()
Activity: Chymotrypsin, with EC number 3.4.21.1
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



STRUCTURE OF ALPHA-*CHYMOTRYPSIN REFINED AT 1.68 ANGSTROMS RESOLUTION

Template:ABSTRACT PUBMED 4046030

About this Structure

4CHA is a Protein complex structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

Structure of alpha-chymotrypsin refined at 1.68 A resolution., Tsukada H, Blow DM, J Mol Biol. 1985 Aug 20;184(4):703-11. PMID:4046030

Page seeded by OCA on Thu Jul 3 13:32:09 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4cha"
Personal tools