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1dxm
From Proteopedia
(New page: 200px<br /> <applet load="1dxm" size="450" color="white" frame="true" align="right" spinBox="true" caption="1dxm, resolution 2.60Å" /> '''REDUCED FORM OF THE...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1DXM is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pisum_sativum Pisum sativum]] with RED as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1DXM OCA]]. | + | 1DXM is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pisum_sativum Pisum sativum]] with RED as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Sites: LP1 and LP2. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1DXM OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: mitochondria]] | [[Category: mitochondria]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:31:28 2007'' |
Revision as of 10:26, 30 October 2007
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REDUCED FORM OF THE H PROTEIN FROM GLYCINE DECARBOXYLASE COMPLEX
Overview
The glycine decarboxylase complex consists of four different component, enzymes (P-, H-, T- and L-proteins). The 14-kDa lipoamide-containing, H-protein plays a pivotal role in the complete sequence of reactions as, its prosthetic group (lipoic acid) interacts successively with the three, other components of the complex and undergoes a cycle of reductive, methylamination, methylamine transfer and electron transfer. With the aim, to understand the interaction between the H-protein and its different, partners, we have previously determined the crystal structure of the, oxidized and methylaminated forms of the H-protein. In the present study, we have crystallized the H-protein in its reduced state and the L-protein, (lipoamide dehydrogenase or dihydrolipoamide dehydrogenase). The L-protein, ... [(full description)]
About this Structure
1DXM is a [Single protein] structure of sequence from [Pisum sativum] with RED as [ligand]. Structure known Active Sites: LP1 and LP2. Full crystallographic information is available from [OCA].
Reference
Interaction between the lipoamide-containing H-protein and the lipoamide dehydrogenase (L-protein) of the glycine decarboxylase multienzyme system 2. Crystal structures of H- and L-proteins., Faure M, Bourguignon J, Neuburger M, MacHerel D, Sieker L, Ober R, Kahn R, Cohen-Addad C, Douce R, Eur J Biochem. 2000 May;267(10):2890-8. PMID:10806386
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