7rsa

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{{STRUCTURE_7rsa| PDB=7rsa | SCENE= }}
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'''STRUCTURE OF PHOSPHATE-FREE RIBONUCLEASE A REFINED AT 1.26 ANGSTROMS'''
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===STRUCTURE OF PHOSPHATE-FREE RIBONUCLEASE A REFINED AT 1.26 ANGSTROMS===
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==Overview==
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The structure of phosphate-free bovine ribonuclease A has been refined at 1.26-A resolution by a restrained least-squares procedure to a final R factor of 0.15. X-ray diffraction data were collected with an electronic position-sensitive detector. The final model consists of all atoms in the polypeptide chain including hydrogens, 188 water sites with full or partial occupancy, and a single molecule of 2-methyl-2-propanol. Thirteen side chains were modeled with two alternate conformations. Major changes to the active site include the addition of two waters in the phosphate-binding pocket, disordering of Gln-11, and tilting of the imidazole ring of His-119. The structure of the protein and of the associated solvent was extensively compared with three other high-resolution, refined structures of this enzyme.
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(as it appears on PubMed at http://www.pubmed.gov), where 3401445 is the PubMed ID number.
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{{ABSTRACT_PUBMED_3401445}}
==About this Structure==
==About this Structure==
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[[Category: Gilliland, G L.]]
[[Category: Gilliland, G L.]]
[[Category: Wlodawer, A.]]
[[Category: Wlodawer, A.]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 15:00:50 2008''

Revision as of 12:00, 3 July 2008

Image:7rsa.png


PDB ID 7rsa

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7rsa, resolution 1.26Å ()
Ligands: ,
Activity: Pancreatic ribonuclease, with EC number 3.1.27.5
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



STRUCTURE OF PHOSPHATE-FREE RIBONUCLEASE A REFINED AT 1.26 ANGSTROMS

Template:ABSTRACT PUBMED 3401445

About this Structure

7RSA is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Structure of phosphate-free ribonuclease A refined at 1.26 A., Wlodawer A, Svensson LA, Sjolin L, Gilliland GL, Biochemistry. 1988 Apr 19;27(8):2705-17. PMID:3401445

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