1qj8
From Proteopedia
(New page: 200px<br /> <applet load="1qj8" size="450" color="white" frame="true" align="right" spinBox="true" caption="1qj8, resolution 1.9Å" /> '''CRYSTAL STRUCTURE OF...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1QJ8 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with C8E and PCL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QJ8 OCA]]. | + | 1QJ8 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with C8E and PCL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Sites: PC1 and PC2. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QJ8 OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: platinum complex structure]] | [[Category: platinum complex structure]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:32:19 2007'' |
Revision as of 10:27, 30 October 2007
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CRYSTAL STRUCTURE OF THE OUTER MEMBRANE PROTEIN OMPX FROM ESCHERICHIA COLI
Overview
BACKGROUND: The integral outer membrane protein X (OmpX) from Escherichia, coli belongs to a family of highly conserved bacterial proteins that, promote bacterial adhesion to and entry into mammalian cells. Moreover, these proteins have a role in the resistance against attack by the human, complement system. Here we present the first crystal structure of a member, of this family. RESULTS: The crystal structure of OmpX from E. coli was, determined at 1.9 A resolution using multiple isomorphous replacement., OmpX consists of an eight-stranded antiparallel all-next-neighbor beta, barrel. The structure shows two girdles of aromatic amino acid residues, and a ribbon of nonpolar residues that attach to the membrane interior., The core of the barrel consists of an extended hydrogen-bonding ... [(full description)]
About this Structure
1QJ8 is a [Single protein] structure of sequence from [Escherichia coli] with C8E and PCL as [ligands]. Structure known Active Sites: PC1 and PC2. Full crystallographic information is available from [OCA].
Reference
The structure of the outer membrane protein OmpX from Escherichia coli reveals possible mechanisms of virulence., Vogt J, Schulz GE, Structure. 1999 Oct 15;7(10):1301-9. PMID:10545325
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