1qjk

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(New page: 200px<br /> <applet load="1qjk" size="450" color="white" frame="true" align="right" spinBox="true" caption="1qjk" /> '''METALLOTHIONEIN MTA FROM SEA URCHIN (ALPHA ...)
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==About this Structure==
==About this Structure==
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1QJK is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Strongylocentrotus_purpuratus Strongylocentrotus purpuratus]] with CD as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QJK OCA]].
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1QJK is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Strongylocentrotus_purpuratus Strongylocentrotus purpuratus]] with CD as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: CD4. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QJK OCA]].
==Reference==
==Reference==
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[[Category: radical scavenger]]
[[Category: radical scavenger]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 19:24:52 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:32:56 2007''

Revision as of 10:28, 30 October 2007


1qjk

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METALLOTHIONEIN MTA FROM SEA URCHIN (ALPHA DOMAIN)

Overview

The three-dimensional structure of [(113)Cd7]-metallothionein-A (MTA) of, the sea urchin Strongylocentrotus purpuratus was determined by, homonuclear(1)H NMR experiments and heteronuclear [(1)H, (113)Cd]-correlation spectroscopy. MTA is composed of two globular, domains, an N-terminal four-metal domain of the amino acid residues 1 to, 36 and a Cd4Cys11cluster, and a C-terminal three-metal domain including, the amino acid residues 37 to 65 and a Cd3Cys9cluster. The structure, resembles the known mammalian and crustacean metallothioneins, but has a, significantly different connectivity pattern of the Cys-metal, co-ordination bonds and concomitantly contains novel local folds of some, polypeptide backbone segments. These differences can be related to, variations of the Cys sequence positions ... [(full description)]

About this Structure

1QJK is a [Single protein] structure of sequence from [Strongylocentrotus purpuratus] with CD as [ligand]. Structure known Active Site: CD4. Full crystallographic information is available from [OCA].

Reference

NMR structure of the sea urchin (Strongylocentrotus purpuratus) metallothionein MTA., Riek R, Precheur B, Wang Y, Mackay EA, Wider G, Guntert P, Liu A, Kagi JH, Wuthrich K, J Mol Biol. 1999 Aug 13;291(2):417-28. PMID:10438629

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