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3ci0

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{{STRUCTURE_3ci0| PDB=3ci0 | SCENE= }}
{{STRUCTURE_3ci0| PDB=3ci0 | SCENE= }}
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'''The Crystal Structure of the GspK-GspI-GspJ complex from enterotoxigenic Escherichia coli Type 2 Secretion System'''
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===The Crystal Structure of the GspK-GspI-GspJ complex from enterotoxigenic Escherichia coli Type 2 Secretion System===
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==Overview==
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Gram-negative bacteria translocate various proteins including virulence factors across their outer membrane via type 2 secretion systems (T2SSs). T2SSs are thought to contain a pseudopilus, a subcomplex formed by one major and several minor pseudopilins. We report the crystal structure of the complex formed by three minor pseudopilins from enterotoxigenic Escherichia coli. The GspK-GspI-GspJ complex has quasihelical characteristics and an architecture consistent with a localization at the pseudopilus tip. The alpha-domain of GspK has a previously unobserved fold with an unexpected dinuclear metal binding site. The area surrounding its disulfide bridge is conserved and might interact with other T2SS components or with secreted proteins.
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(as it appears on PubMed at http://www.pubmed.gov), where 18438417 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18438417}}
==About this Structure==
==About this Structure==
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[[Category: Pseudopilus]]
[[Category: Pseudopilus]]
[[Category: Type 4 pilin biogenesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 07:39:53 2008''

Revision as of 04:39, 28 July 2008

Image:3ci0.png

Template:STRUCTURE 3ci0

The Crystal Structure of the GspK-GspI-GspJ complex from enterotoxigenic Escherichia coli Type 2 Secretion System

Template:ABSTRACT PUBMED 18438417

About this Structure

3CI0 is a Protein complex structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structure of the GspK-GspI-GspJ complex from the enterotoxigenic Escherichia coli type 2 secretion system., Korotkov KV, Hol WG, Nat Struct Mol Biol. 2008 May;15(5):462-8. Epub 2008 Apr 27. PMID:18438417

Page seeded by OCA on Mon Jul 28 07:39:53 2008

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