1hjz
From Proteopedia
(New page: 200px<br /> <applet load="1hjz" size="450" color="white" frame="true" align="right" spinBox="true" caption="1hjz, resolution 1.7Å" /> '''CRYSTAL STRUCTURE OF...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1HJZ is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]] with MES as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1HJZ OCA]]. | + | 1HJZ is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus]] with MES as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1HJZ OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: histone macroh2a]] | [[Category: histone macroh2a]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:34:44 2007'' |
Revision as of 10:30, 30 October 2007
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CRYSTAL STRUCTURE OF AF1521 PROTEIN CONTAINING A MACROH2A DOMAIN
Overview
MacroH2A is an unusual histone H2A variant that has an extensive, C-terminal tail that comprises approximately two thirds of the protein., The C-terminal non-histone domain of macroH2A is also found in a number of, other proteins and has been termed the macro domain. Here we report the, crystal structure to 1.7A of AF1521, a protein consisting of a stand-alone, macro domain from Archaeoglobus fulgidus. The structure has a mixed, alpha/beta fold that closely resembles the N-terminal DNA binding domain, of the Escherichia coli leucine aminopeptidase PepA. The structure also, shows some similarity to members of the P-loop family of nucleotide, hydrolases.
About this Structure
1HJZ is a [Single protein] structure of sequence from [Archaeoglobus fulgidus] with MES as [ligand]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A., Allen MD, Buckle AM, Cordell SC, Lowe J, Bycroft M, J Mol Biol. 2003 Jul 11;330(3):503-11. PMID:12842467
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