2r2m

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(New page: '''Unreleased structure''' The entry 2r2m is ON HOLD Authors: Spurlino, J. Description: 2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors ''Page seeded by [http://o...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:2r2m.jpg|left|200px]]
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The entry 2r2m is ON HOLD
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{{STRUCTURE_2r2m| PDB=2r2m | SCENE= }}
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Authors: Spurlino, J.
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===2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors===
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Description: 2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors
 
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{{ABSTRACT_PUBMED_17889527}}
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 08:46:58 2008''
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==Disease==
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Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]
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==About this Structure==
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2R2M is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2M OCA].
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==Reference==
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2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors., Lee L, Kreutter KD, Pan W, Crysler C, Spurlino J, Player MR, Tomczuk B, Lu T, Bioorg Med Chem Lett. 2007 Nov 15;17(22):6266-9. Epub 2007 Sep 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17889527 17889527]
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[[Category: Hirudo medicinalis]]
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[[Category: Homo sapiens]]
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[[Category: Protein complex]]
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[[Category: Thrombin]]
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[[Category: Spurlino, J.]]
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[[Category: Acute phase]]
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[[Category: Blood coagulation]]
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[[Category: Calcium]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Disease mutation]]
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[[Category: Gamma-carboxyglutamic acid]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Kringle]]
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[[Category: Polymorphism]]
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[[Category: Protease]]
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[[Category: Protease inhibitor]]
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[[Category: Secreted]]
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[[Category: Serine protease]]
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[[Category: Serine protease inhibitor]]
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[[Category: Sulfation]]
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[[Category: Thrombin]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 11:08:24 2008''

Revision as of 08:08, 27 August 2008

Template:STRUCTURE 2r2m

Contents

2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors

Template:ABSTRACT PUBMED 17889527

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

2R2M is a Protein complex structure of sequences from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

Reference

2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors., Lee L, Kreutter KD, Pan W, Crysler C, Spurlino J, Player MR, Tomczuk B, Lu T, Bioorg Med Chem Lett. 2007 Nov 15;17(22):6266-9. Epub 2007 Sep 8. PMID:17889527

Page seeded by OCA on Wed Aug 27 11:08:24 2008

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