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2r2m
From Proteopedia
(New page: '''Unreleased structure''' The entry 2r2m is ON HOLD Authors: Spurlino, J. Description: 2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors ''Page seeded by [http://o...) |
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| + | [[Image:2r2m.jpg|left|200px]] | ||
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| + | The line below this paragraph, containing "STRUCTURE_2r2m", creates the "Structure Box" on the page. | ||
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| + | {{STRUCTURE_2r2m| PDB=2r2m | SCENE= }} | ||
| - | + | ===2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors=== | |
| - | Description: 2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors | ||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_17889527}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 17889527 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_17889527}} | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | ==Disease== |
| + | Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]] | ||
| + | |||
| + | ==About this Structure== | ||
| + | 2R2M is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2M OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | 2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors., Lee L, Kreutter KD, Pan W, Crysler C, Spurlino J, Player MR, Tomczuk B, Lu T, Bioorg Med Chem Lett. 2007 Nov 15;17(22):6266-9. Epub 2007 Sep 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17889527 17889527] | ||
| + | [[Category: Hirudo medicinalis]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Protein complex]] | ||
| + | [[Category: Thrombin]] | ||
| + | [[Category: Spurlino, J.]] | ||
| + | [[Category: Acute phase]] | ||
| + | [[Category: Blood coagulation]] | ||
| + | [[Category: Calcium]] | ||
| + | [[Category: Cleavage on pair of basic residue]] | ||
| + | [[Category: Disease mutation]] | ||
| + | [[Category: Gamma-carboxyglutamic acid]] | ||
| + | [[Category: Glycoprotein]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Kringle]] | ||
| + | [[Category: Polymorphism]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: Protease inhibitor]] | ||
| + | [[Category: Secreted]] | ||
| + | [[Category: Serine protease]] | ||
| + | [[Category: Serine protease inhibitor]] | ||
| + | [[Category: Sulfation]] | ||
| + | [[Category: Thrombin]] | ||
| + | [[Category: Zymogen]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 11:08:24 2008'' | ||
Revision as of 08:08, 27 August 2008
Contents |
2-(2-Chloro-6-Fluorophenyl)Acetamides as Potent Thrombin Inhibitors
Template:ABSTRACT PUBMED 17889527
Disease
Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]
About this Structure
2R2M is a Protein complex structure of sequences from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
Reference
2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors., Lee L, Kreutter KD, Pan W, Crysler C, Spurlino J, Player MR, Tomczuk B, Lu T, Bioorg Med Chem Lett. 2007 Nov 15;17(22):6266-9. Epub 2007 Sep 8. PMID:17889527
Page seeded by OCA on Wed Aug 27 11:08:24 2008
Categories: Hirudo medicinalis | Homo sapiens | Protein complex | Thrombin | Spurlino, J. | Acute phase | Blood coagulation | Calcium | Cleavage on pair of basic residue | Disease mutation | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Kringle | Polymorphism | Protease | Protease inhibitor | Secreted | Serine protease | Serine protease inhibitor | Sulfation | Zymogen
