3ce3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: '''Unreleased structure''' The entry 3ce3 is ON HOLD until Paper Publication Authors: Sack, J. Description: Crystal structure of the tyrosine kinase domain of the hepatocyte growth fac...)
Line 1: Line 1:
-
'''Unreleased structure'''
+
{{Seed}}
 +
[[Image:3ce3.jpg|left|200px]]
-
The entry 3ce3 is ON HOLD until Paper Publication
+
<!--
 +
The line below this paragraph, containing "STRUCTURE_3ce3", creates the "Structure Box" on the page.
 +
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 +
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 +
or leave the SCENE parameter empty for the default display.
 +
-->
 +
{{STRUCTURE_3ce3| PDB=3ce3 | SCENE= }}
-
Authors: Sack, J.
+
===Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor C-MET in complex with a Pyrrolopyridinepyridone based inhibitor===
-
Description: Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor C-MET in complex with a Pyrrolopyridinepyridone based inhibitor
 
 +
<!--
 +
The line below this paragraph, {{ABSTRACT_PUBMED_18690676}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 18690676 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_18690676}}
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 09:31:33 2008''
+
==Disease==
 +
Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Renal cell carcinoma, papillary, familial and sporadic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Autism, suseptibility to, 9 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]]
 +
 
 +
==About this Structure==
 +
3CE3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CE3 OCA].
 +
 
 +
==Reference==
 +
Discovery of Pyrrolopyridine-Pyridone Based Inhibitors of Met Kinase: Synthesis, X-ray Crystallographic Analysis, and Biological Activities., Kim KS, Zhang L, Schmidt R, Cai ZW, Wei D, Williams DK, Lombardo LJ, Trainor GL, Xie D, Zhang Y, An Y, Sack JS, Tokarski JS, Darienzo C, Kamath A, Marathe P, Zhang Y, Lippy J, Jeyaseelan R Sr, Wautlet B, Henley B, Gullo-Brown J, Manne V, Hunt JT, Fargnoli J, Borzilleri RM, J Med Chem. 2008 Aug 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18690676 18690676]
 +
[[Category: Homo sapiens]]
 +
[[Category: Receptor protein-tyrosine kinase]]
 +
[[Category: Single protein]]
 +
[[Category: Sack, J.]]
 +
[[Category: Atp-binding]]
 +
[[Category: Glycoprotein]]
 +
[[Category: Grb2]]
 +
[[Category: Membrane]]
 +
[[Category: Nucleotide-binding]]
 +
[[Category: Phosphoprotein]]
 +
[[Category: Proto-oncogene]]
 +
[[Category: Receptor tyrosine kinase]]
 +
[[Category: Shc]]
 +
[[Category: Signal transduction]]
 +
[[Category: Transferase]]
 +
[[Category: Transmembrane]]
 +
[[Category: Tyrosine-protein kinase]]
 +
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 11:24:39 2008''

Revision as of 08:24, 27 August 2008

Image:3ce3.jpg

Template:STRUCTURE 3ce3

Contents

Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor C-MET in complex with a Pyrrolopyridinepyridone based inhibitor

Template:ABSTRACT PUBMED 18690676

Disease

Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[164860], Renal cell carcinoma, papillary, familial and sporadic OMIM:[164860], Autism, suseptibility to, 9 OMIM:[164860]

About this Structure

3CE3 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Discovery of Pyrrolopyridine-Pyridone Based Inhibitors of Met Kinase: Synthesis, X-ray Crystallographic Analysis, and Biological Activities., Kim KS, Zhang L, Schmidt R, Cai ZW, Wei D, Williams DK, Lombardo LJ, Trainor GL, Xie D, Zhang Y, An Y, Sack JS, Tokarski JS, Darienzo C, Kamath A, Marathe P, Zhang Y, Lippy J, Jeyaseelan R Sr, Wautlet B, Henley B, Gullo-Brown J, Manne V, Hunt JT, Fargnoli J, Borzilleri RM, J Med Chem. 2008 Aug 9. PMID:18690676

Page seeded by OCA on Wed Aug 27 11:24:39 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3ce3"
Personal tools